STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpCKEGG: cac:CAC3160 2.3e-52 trpC; indole-3-glycerol phosphate synthase K01609; COG: COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (260 aa)    
Predicted Functional Partners:
EDS76068.1
Chorismate binding enzyme; KEGG: aae:aq_582 1.8e-100 trpE; anthranilate synthase component I K01657; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score: 8.87.
 
 0.999
trpF
KEGG: cac:CAC3159 2.2e-40 trpF; phosphoribosylanthranilate isomerase K01817; COG: COG0135 Phosphoribosylanthranilate isomerase; Belongs to the TrpF family.
 
 0.999
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 0.999
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
 0.999
EDS76069.1
Glutamine amidotransferase, class I; KEGG: tte:TTE1582 3.1e-57 pabA; anthranilate/para-aminobenzoate synthases component II K01658; COG: COG0512 Anthranilate/para-aminobenzoate synthases component II; Psort location: Cytoplasmic, score: 8.87.
  
 0.998
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
  
 0.998
trpC-2
KEGG: chy:CHY_1584 6.0e-47 trpC; indole-3-glycerol phosphate synthase K01609; COG: COG0134 Indole-3-glycerol phosphate synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the TrpC family.
  
  
 
0.905
EDS74218.1
Chorismate mutase; KEGG: aae:aq_951 3.3e-53 pheA; chorismate mutase/prephenate dehydratase K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score: 9.98.
  
  
 0.610
EDS75817.1
Class II glutamine amidotransferase; KEGG: syn:sll1502 0. gltB; NADH-dependent glutamate synthase large subunit K00268; COG: COG0069 Glutamate synthase domain 2; Psort location: Cytoplasmic, score: 8.87.
     
 0.587
hisE
phosphoribosyl-ATP diphosphatase; KEGG: lla:L0072 1.5e-80 hisI; phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase K01496:K01523; COG: COG0139 Phosphoribosyl-AMP cyclohydrolase; Psort location: Cytoplasmic, score: 9.98; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.583
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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