STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS76098.1EDD domain protein, DegV family; COG: COG1307 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. (293 aa)    
Predicted Functional Partners:
EDS75459.1
DAK2 domain fusion protein YloV; KEGG: bcz:BCZK3615 4.2e-133 dhaK; possible dihydroxyacetone-related kinase K00863; COG: COG1461 Predicted kinase related to dihydroxyacetone kinase; Psort location: Cytoplasmic, score: 8.87.
 
 0.974
luxS
S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
       0.773
rex
CoA binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
  
   
 0.657
EDS76099.1
Putative YigZ family protein; KEGG: spi:MGAS10750_Spy1437 6.8e-30 Xaa-Pro dipeptidase K01271; COG: COG1739 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
       0.570
EDS75460.1
COG: COG1302 Uncharacterized protein conserved in bacteria.
 
    0.518
EDS76100.1
dUTP diphosphatase; COG: COG4508 Uncharacterized protein conserved in bacteria.
  
    0.452
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (30%) [HD]