STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pulAPullulanase, type I; KEGG: btk:BT9727_4434 8.9e-124 amyX; pullulanase K01200; COG: COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; Psort location: Cytoplasmic, score: 9.98; Belongs to the glycosyl hydrolase 13 family. (694 aa)    
Predicted Functional Partners:
glgD
KEGG: cpr:CPR_0087 2.1e-67 glgD; glucose-1-phosphate adenylyltransferase, GlgD subunit K00975; COG: COG0448 ADP-glucose pyrophosphorylase; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.979
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
 
 
 0.978
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
 
0.976
glgP
Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
 
 
 0.959
glgA
Glycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
 
 
 0.953
malQ
4-alpha-glucanotransferase; KEGG: ftl:FTL_0488 6.0e-118 4-alpha-glucanotransferase K00705; COG: COG1640 4-alpha-glucanotransferase; Psort location: Cytoplasmic, score: 9.98.
 
 0.928
EDS76122.1
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: gka:GK3297 1.2e-151 phosphomannomutase K01840; COG: COG1109 Phosphomannomutase; Psort location: Cytoplasmic, score: 8.87.
    
 0.875
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
       0.775
pth
aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
       0.770
galU
KEGG: ctc:CTC02269 4.2e-94 UTP-glucose-1-phosphate uridylyltransferase K00963; COG: COG1210 UDP-glucose pyrophosphorylase; Psort location: Cytoplasmic, score: 8.87.
    
 0.681
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.