STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS76130.1Hypothetical protein; COG: NOG10763 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.87. (473 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
    
  0.855
EDS76129.1
Hypothetical protein; KEGG: btk:BT9727_2838 4.2e-18 methyltransferase K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: CytoplasmicMembrane, score: 7.63.
       0.773
EDS73729.1
HD domain protein; COG: NOG14059 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
 0.695
spoIIAB
Anti-sigma F factor; KEGG: cpr:CPR_2021 9.4e-33 spoIIAB; anti-sigma F factor K06379; COG: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); Psort location: Cytoplasmic, score: 8.87.
   
 
 0.627
EDS74451.1
Hypothetical protein; KEGG: fal:FRAAL1277 1.4e-06 serine/threonine-protein kinase (switch protein/serine kinase) (anti-sigma B factor RsbT) K08282; COG: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); Psort location: Cytoplasmic, score: 8.87.
   
 
 0.627
EDS75148.1
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.602
purH
KEGG: cpf:CPF_0677 2.0e-133 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602:K01492; COG: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); Psort location: Cytoplasmic, score: 8.87.
   
 
  0.595
EDS74818.1
KEGG: lmf:LMOf2365_0150 3.1e-215 inosine-5'-monophosphate dehydrogenase, putative K00088; COG: COG0516 IMP dehydrogenase/GMP reductase; Psort location: Cytoplasmic, score: 8.87.
    
  0.592
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
  0.591
EDS75827.1
Response regulator receiver domain protein; KEGG: ava:Ava_2028 2.1e-42 two component transcriptional regulator, LuxR family; COG: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; Psort location: Cytoplasmic, score: 9.65.
  
 
 0.536
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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