Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
EDS75992.1Hypothetical protein; KEGG: fnu:FN1984 0.00068 thioredoxin reductase / glutaredoxin-like protein K00384; COG: COG0526 Thiol-disulfide isomerase and thioredoxins; Psort location: Cytoplasmic, score: 8.87. (105 aa)    
Predicted Functional Partners:
ahpC
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 0.963
EDS75711.1
Hypothetical protein; KEGG: bcc:BCc_107 0.0071 nuoL; NADH dehydrogenase I chain L K00329; COG: NOG17674 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
   
 0.947
EDS75993.1
Putative permease; KEGG: rbe:RBE_0088 0.0082 nuoM; NADH dehydrogenase I chain M K00342; COG: COG0701 Predicted permeases; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.909
EDS74806.1
Putative thioredoxin-disulfide reductase; KEGG: cpe:CPE0783 1.3e-122 probable thioredoxin reductase K00384; COG: COG0526 Thiol-disulfide isomerase and thioredoxins; Psort location: Cytoplasmic, score: 9.65.
  
 
 0.840
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.787
dnaK-2
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.787
EDS75763.1
Hypothetical protein; KEGG: pub:SAR11_0453 8.8e-05 aroK; shikimate kinase K00891.
  
 0.786
trxB
KEGG: bcl:ABC3038 3.0e-84 trxB; thioredoxin reductase K00384; COG: COG0492 Thioredoxin reductase; Psort location: Cytoplasmic, score: 9.65.
  
 
 0.767
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
 0.762
EDS74568.1
DnaJ domain protein; COG: COG2214 DnaJ-class molecular chaperone; Psort location: Cytoplasmic, score: 9.65.
    
 0.762
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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