STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS76000.1PhoH family protein; KEGG: reh:H16_A0527 7.2e-74 phoH; phosphate starvation-inducible protein PhoH,predicted ATPase; COG: COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase; Psort location: Cytoplasmic, score: 9.98. (318 aa)    
Predicted Functional Partners:
ybeY
Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.885
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
  
 0.862
EDS76002.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ban:BA4832 1.4e-56 phoR; sensory box histidine kinase PhoR K07636; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
  
  
 0.809
EDS75999.1
Putative sporulation protein YqfD; COG: NOG07866 non supervised orthologous group.
       0.799
EDS76001.1
Response regulator receiver domain protein; KEGG: ava:Ava_1878 6.2e-36 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
  
  
 0.791
EDS75998.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.773
rpsU
COG: COG0828 Ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
       0.632
era
Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
 
  
 0.597
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
 
     0.568
sun
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
 
    0.538
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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