STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS76003.1Trypsin; KEGG: bsu:BG11054 1.1e-70 yyxA, yycK; similar to serine protease Do; COG: COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. (532 aa)    
Predicted Functional Partners:
EDS75957.1
KEGG: tma:TM1430 1.5e-21 glycerol kinase K00864; COG: COG0554 Glycerol kinase; Psort location: Cytoplasmic, score: 8.87.
   
 0.948
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
    
 0.833
phnW
2-aminoethylphosphonate--pyruvate transaminase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
    
  0.829
ilvB
KEGG: chy:CHY_0517 2.1e-163 ilvB1; acetolactate synthase, large subunit, biosynthetic type K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score: 8.87.
     
 0.827
alaS
alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 
 0.825
EDS74574.1
FAD dependent oxidoreductase; KEGG: mma:MM1656 1.6e-55 oxidoreductase K00100; COG: COG0665 Glycine/D-amino acid oxidases (deaminating); Psort location: Cytoplasmic, score: 8.87.
  
 0.803
EDS74205.1
Hypothetical protein; KEGG: lla:L0022 0.0026 kdgA; 2-dehydro-3-deoxyphosphogluconate aldolase / 4-hydroxy-2-oxoglutarate aldolase K01625:K01650; COG: NOG09943 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
    
 0.786
EDS73879.1
Peptidase, S41 family; KEGG: gka:GK3092 7.3e-65 carboxyl-terminal processing protease; COG: COG0793 Periplasmic protease; Belongs to the peptidase S41A family.
 
  
 0.778
EDS75763.1
Hypothetical protein; KEGG: pub:SAR11_0453 8.8e-05 aroK; shikimate kinase K00891.
    
 0.729
EDS75415.1
Hydrolase, NUDIX family; KEGG: bsu:BG11762 8.0e-36 nudF, yqkG; ADP-ribose pyrophosphatase K01515; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: Cytoplasmic, score: 8.87.
    
 0.727
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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