STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cmkCytidylate kinase; KEGG: bca:BCE_1623 2.5e-55 cmk; cytidylate kinase K00945; COG: COG0283 Cytidylate kinase; Psort location: Cytoplasmic, score: 8.87. (222 aa)    
Predicted Functional Partners:
der
Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
 0.994
EDS75227.1
KEGG: cno:NT01CX_0626 1.1e-70 prephenate dehydrogenase K00210; COG: COG0287 Prephenate dehydrogenase; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.945
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 
 0.936
EDS74218.1
Chorismate mutase; KEGG: aae:aq_951 3.3e-53 pheA; chorismate mutase/prephenate dehydratase K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.929
scpB
Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
  
 0.918
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
      0.907
ribF
KEGG: bar:GBAA3946 2.6e-60 ribC; riboflavin biosynthesis protein RibC K00861:K00953; COG: COG0196 FAD synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the ribF family.
  
 0.892
EDS75098.1
Cytidine and deoxycytidylate deaminase zinc-binding region; KEGG: fnu:FN1902 5.3e-55 deoxycytidylate deaminase K01493; COG: COG2131 Deoxycytidylate deaminase; Psort location: Cytoplasmic, score: 8.87.
    
  0.850
EDS74201.1
Pseudouridylate synthase; KEGG: sha:SH1423 2.9e-63 rluB; ribosomal large subunit pseudouridine synthase B K06178; COG: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Psort location: Cytoplasmic, score: 8.87; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.839
gpsA
KEGG: bce:BC1505 5.7e-74 gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase K00057; COG: COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.796
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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