STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS76022.1Conserved hypothetical protein TIGR03905; COG: NOG17478 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (90 aa)    
Predicted Functional Partners:
EDS76021.1
TRAM domain protein; KEGG: bsu:BG12911 7.9e-52 yfjO; similar to RNA methyltransferase K00599; COG: COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Psort location: Cytoplasmic, score: 8.87; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
       0.773
EDS76023.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
       0.563
EDS76020.1
Putative stage V sporulation protein D; KEGG: swo:Swol_0820 2.2e-100 peptidoglycan glycosyltransferase K05364; COG: COG0768 Cell division protein FtsI/penicillin-binding protein 2; Psort location: CytoplasmicMembrane, score: 9.49.
       0.504
EDS75528.1
Rubredoxin; KEGG: cpr:CPR_0938 9.4e-10 periplasmic [Fe] hydrogenase 1 K00532; COG: COG1592 Rubrerythrin; Psort location: Cytoplasmic, score: 8.87.
  
     0.451
EDS76024.1
KEGG: btk:BT9727_4333 1.5e-215 dnaE; DNA polymerase III, alpha subunit K02337; COG: COG0587 DNA polymerase III, alpha subunit; Psort location: Cytoplasmic, score: 9.98.
       0.441
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
       0.441
mutM
DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.438
EDS76027.1
Oxidoreductase, NAD-binding domain protein; KEGG: hsa:27294 3.1e-27 DHDH; dihydrodiol dehydrogenase (dimeric) K00212; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score: 8.87.
       0.438
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.438
EDS76029.1
KEGG: sph:MGAS10270_Spy0282 3.5e-05 dnaB; replicative DNA helicase K01529; COG: COG3611 Replication initiation/membrane attachment protein; Psort location: Cytoplasmic, score: 8.87.
       0.438
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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