STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS76027.1Oxidoreductase, NAD-binding domain protein; KEGG: hsa:27294 3.1e-27 DHDH; dihydrodiol dehydrogenase (dimeric) K00212; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score: 8.87. (316 aa)    
Predicted Functional Partners:
tagD
KEGG: bld:BLi03818 1.2e-50 tagD; glycerol-3-phosphate cytidylyltransferase; RBL05030 K00980; COG: COG0615 Cytidylyltransferase; Psort location: Cytoplasmic, score: 9.98.
 
    0.899
tagD-2
KEGG: bcl:ABC3101 5.6e-51 tagD; glycerol-3-phosphate cytidylyltransferase K00980; COG: COG0615 Cytidylyltransferase; Psort location: Cytoplasmic, score: 9.98.
 
    0.897
EDS75394.1
DegT/DnrJ/EryC1/StrS aminotransferase family protein; KEGG: cno:NT01CX_1463 6.9e-101 spsC; spore coat polysaccharide biosynthesis protein SpsC K01726; COG: COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Psort location: Cytoplasmic, score: 8.87; Belongs to the DegT/DnrJ/EryC1 family.
 
 
 0.789
EDS76024.1
KEGG: btk:BT9727_4333 1.5e-215 dnaE; DNA polymerase III, alpha subunit K02337; COG: COG0587 DNA polymerase III, alpha subunit; Psort location: Cytoplasmic, score: 9.98.
       0.775
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.775
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
    0.774
mutM
DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.774
EDS76029.1
KEGG: sph:MGAS10270_Spy0282 3.5e-05 dnaB; replicative DNA helicase K01529; COG: COG3611 Replication initiation/membrane attachment protein; Psort location: Cytoplasmic, score: 8.87.
       0.773
EDS76030.1
Primosomal protein DnaI; KEGG: spi:MGAS10750_Spy1680 1.3e-06 replicative DNA helicase K01529; COG: COG1484 DNA replication protein.
       0.762
EDS75723.1
Aldehyde dehydrogenase (NAD) family protein; KEGG: ctc:CTC02523 8.9e-108 ywdH; putative aldehyde dehydrogenase YwdH K00128; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.704
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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