STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)    
Predicted Functional Partners:
pyk-2
Pyruvate kinase; KEGG: ssp:SSP1069 2.9e-125 pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
 
 0.970
pgi
KEGG: bli:BL02591 3.9e-137 pgi; glucose-6-phosphate isomerase K01810; COG: COG0166 Glucose-6-phosphate isomerase; Psort location: Cytoplasmic, score: 9.98; Belongs to the GPI family.
  
 0.960
pyk
Pyruvate kinase; KEGG: oih:OB2171 3.5e-129 pykA; pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
 
 0.923
EDS75666.1
KEGG: chy:CHY_0128 4.3e-76 fba; fructose-1,6-bisphosphate aldolase, class II K01624; COG: COG0191 Fructose/tagatose bisphosphate aldolase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.922
fba
KEGG: cpf:CPF_1557 3.4e-115 fba; fructose-1,6-bisphosphate aldolase, class II K01624; COG: COG0191 Fructose/tagatose bisphosphate aldolase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.922
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.914
pfkB
1-phosphofructokinase; KEGG: cno:NT01CX_1725 1.1e-79 1-phosphofructokinase K00882; COG: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Psort location: Cytoplasmic, score: 8.87; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
     
 0.911
EDS75665.1
Tagatose-6-phosphate kinase; KEGG: yps:YPTB3076 9.3e-97 agaZ; putative tagatose 6-phosphate kinase K00917; COG: COG4573 Predicted tagatose 6-phosphate kinase.
     
 0.903
manA
KEGG: cno:NT01CX_1588 2.0e-62 manA; mannose-6-phosphate isomerase, class I K01809; COG: COG1482 Phosphomannose isomerase; Psort location: Cytoplasmic, score: 8.87.
    
 0.903
EDS75662.1
Sugar isomerase, AgaS family; KEGG: ppr:PBPRB0142 1.4e-84 putative phosphosugar isomerase K02082; COG: COG2222 Predicted phosphosugar isomerases; Psort location: Cytoplasmic, score: 8.87.
    
 0.901
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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