STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75647.1KEGG: spd:SPD_1920 1.7e-19 peptidase, S54 (rhomboid) family protein; COG: COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid); Psort location: CytoplasmicMembrane, score: 9.99. (193 aa)    
Predicted Functional Partners:
EDS75771.1
SPFH/Band 7/PHB domain protein; KEGG: reh:H16_A2036 1.4e-52 membrane protease subunits, stomatin/prohibitin homologs K01423; COG: COG0330 Membrane protease subunits, stomatin/prohibitin homologs; Psort location: Cytoplasmic, score: 8.87.
   
 0.838
EDS75646.1
Hypothetical protein; KEGG: cpr:CPR_0949 9.9e-09 chitinase B K01183; COG: COG3469 Chitinase.
       0.769
EDS73880.1
KEGG: bce:BC4687 6.1e-45 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG0860 N-acetylmuramoyl-L-alanine amidase; Psort location: Cytoplasmic, score: 8.87.
  
   0.728
EDS75724.1
KEGG: sth:STH3039 2.0e-32 N-acetylmuramoyl-L-alanine amidase K01448; COG: COG0860 N-acetylmuramoyl-L-alanine amidase; Psort location: Cytoplasmic, score: 8.87.
  
   0.651
hflB
ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 
 0.536
EDS75273.1
KEGG: baa:BA_4936 1.1e-29 5-formyltetrahydrofolate cyclo-ligase family K01934; COG: COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
  
    0.523
EDS75648.1
Cof-like hydrolase; KEGG: btl:BALH_4896 1.8e-52 hydrolase, haloacid dehalogenase-like family K01564; COG: COG0561 Predicted hydrolases of the HAD superfamily.
  
    0.504
EDS75649.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.487
ispF
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
       0.477
gltX
glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
       0.459
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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