STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75648.1Cof-like hydrolase; KEGG: btl:BALH_4896 1.8e-52 hydrolase, haloacid dehalogenase-like family K01564; COG: COG0561 Predicted hydrolases of the HAD superfamily. (272 aa)    
Predicted Functional Partners:
EDS75649.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.773
EDS75583.1
HAD hydrolase, family IIB; KEGG: sak:SAK_0393 1.9e-15 Cof-like hydrolase/peptidyl-prolyl cis-trans isomerase domain protein; COG: COG0561 Predicted hydrolases of the HAD superfamily.
  
     0.692
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
       0.560
EDS75647.1
KEGG: spd:SPD_1920 1.7e-19 peptidase, S54 (rhomboid) family protein; COG: COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid); Psort location: CytoplasmicMembrane, score: 9.99.
  
    0.504
EDS74966.1
PHP domain protein; KEGG: reh:H16_A1200 1.8e-20 predicted metal-dependent phosphoesterase (PHP family); COG: COG0613 Predicted metal-dependent phosphoesterases (PHP family); Psort location: Cytoplasmic, score: 8.87.
 
      0.485
EDS75646.1
Hypothetical protein; KEGG: cpr:CPR_0949 9.9e-09 chitinase B K01183; COG: COG3469 Chitinase.
       0.484
EDS75804.1
KEGG: efa:EF0020 4.3e-131 PTS system, mannose-specific IIAB components K02793:K02794; COG: COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; Psort location: Cytoplasmic, score: 9.98.
    
  0.448
EDS73783.1
KEGG: efa:EF0020 4.3e-131 PTS system, mannose-specific IIAB components K02793:K02794; COG: COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; Psort location: Cytoplasmic, score: 9.98.
    
  0.448
EDS74624.1
KEGG: sak:SAK_0393 6.1e-22 Cof-like hydrolase/peptidyl-prolyl cis-trans isomerase domain protein; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87.
  
 
 
0.425
EDS75327.1
KEGG: lwe:lwe2649 1.2e-18 Cof-like hydrolase K01564; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87.
  
 
 
0.423
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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