Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
EDS75662.1Sugar isomerase, AgaS family; KEGG: ppr:PBPRB0142 1.4e-84 putative phosphosugar isomerase K02082; COG: COG2222 Predicted phosphosugar isomerases; Psort location: Cytoplasmic, score: 8.87. (395 aa)    
Predicted Functional Partners:
EDS75661.1
PTS system fructose IIA component; KEGG: ppr:PBPRB0146 3.3e-21 putative PTS permease protein K02744; COG: COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.988
EDS75829.1
KEGG: cac:CAC1457 6.4e-34 PTS system, fructose(mannose)-specific IIA component K02744; COG: COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.909
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.901
pfkA-2
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
    
 0.901
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
    
 0.901
EDS74054.1
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family.
    
 0.901
EDS75665.1
Tagatose-6-phosphate kinase; KEGG: yps:YPTB3076 9.3e-97 agaZ; putative tagatose 6-phosphate kinase K00917; COG: COG4573 Predicted tagatose 6-phosphate kinase.
 
  
 0.808
nagA
KEGG: efa:EF3044 3.0e-75 nagA-2; N-acetylglucosamine-6-phosphate deacetylase K01443; COG: COG1820 N-acetylglucosamine-6-phosphate deacetylase.
 
  
 0.798
yajC
Preprotein translocase, YajC subunit; Psort location: CytoplasmicMembrane, score: 9.75.
       0.790
EDS75656.1
KEGG: eci:UTI89_C3570 8.0e-36 agaC; PTS system, N-acetylgalactosamine-specific IIC component 1 K02746; COG: COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.789
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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