Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDS75665.1Tagatose-6-phosphate kinase; KEGG: yps:YPTB3076 9.3e-97 agaZ; putative tagatose 6-phosphate kinase K00917; COG: COG4573 Predicted tagatose 6-phosphate kinase. (440 aa)    
Predicted Functional Partners:
EDS75666.1
KEGG: chy:CHY_0128 4.3e-76 fba; fructose-1,6-bisphosphate aldolase, class II K01624; COG: COG0191 Fructose/tagatose bisphosphate aldolase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.955
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
     
 0.903
pfkA-2
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
     
 0.903
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
     
 0.903
EDS74054.1
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family.
     
 0.903
EDS75662.1
Sugar isomerase, AgaS family; KEGG: ppr:PBPRB0142 1.4e-84 putative phosphosugar isomerase K02082; COG: COG2222 Predicted phosphosugar isomerases; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.808
EDS75657.1
KEGG: eci:UTI89_C3571 3.2e-48 agaD; PTS system, N-acetylgalactosamine-specific IID component K02747; COG: COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; Psort location: CytoplasmicMembrane, score: 10.00.
    0.757
EDS75656.1
KEGG: eci:UTI89_C3570 8.0e-36 agaC; PTS system, N-acetylgalactosamine-specific IIC component 1 K02746; COG: COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; Psort location: CytoplasmicMembrane, score: 10.00.
 
    0.745
EDS75675.1
Transcriptional regulator, AraC family; KEGG: bli:BL05281 2.5e-09 adaA; methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC/XylS family) K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: Cytoplasmic, score: 9.98.
  
     0.715
EDS75201.1
Transcriptional regulator, DeoR family; COG: COG1349 Transcriptional regulators of sugar metabolism; Psort location: Cytoplasmic, score: 8.87.
      0.572
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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