| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDS74054.1 | EDS75662.1 | CLOSPI_02480 | CLOSPI_00172 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | Sugar isomerase, AgaS family; KEGG: ppr:PBPRB0142 1.4e-84 putative phosphosugar isomerase K02082; COG: COG2222 Predicted phosphosugar isomerases; Psort location: Cytoplasmic, score: 8.87. | 0.901 |
| EDS74054.1 | EDS75665.1 | CLOSPI_02480 | CLOSPI_00175 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | Tagatose-6-phosphate kinase; KEGG: yps:YPTB3076 9.3e-97 agaZ; putative tagatose 6-phosphate kinase K00917; COG: COG4573 Predicted tagatose 6-phosphate kinase. | 0.903 |
| EDS74054.1 | EDS75666.1 | CLOSPI_02480 | CLOSPI_00176 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | KEGG: chy:CHY_0128 4.3e-76 fba; fructose-1,6-bisphosphate aldolase, class II K01624; COG: COG0191 Fructose/tagatose bisphosphate aldolase; Psort location: Cytoplasmic, score: 8.87. | 0.922 |
| EDS74054.1 | pfkA | CLOSPI_02480 | CLOSPI_00144 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.609 |
| EDS74054.1 | pfkA-2 | CLOSPI_02480 | CLOSPI_00737 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. | 0.911 |
| EDS74054.1 | pfp | CLOSPI_02480 | CLOSPI_01709 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.918 |
| EDS75201.1 | EDS75665.1 | CLOSPI_01029 | CLOSPI_00175 | Transcriptional regulator, DeoR family; COG: COG1349 Transcriptional regulators of sugar metabolism; Psort location: Cytoplasmic, score: 8.87. | Tagatose-6-phosphate kinase; KEGG: yps:YPTB3076 9.3e-97 agaZ; putative tagatose 6-phosphate kinase K00917; COG: COG4573 Predicted tagatose 6-phosphate kinase. | 0.572 |
| EDS75656.1 | EDS75657.1 | CLOSPI_00166 | CLOSPI_00167 | KEGG: eci:UTI89_C3570 8.0e-36 agaC; PTS system, N-acetylgalactosamine-specific IIC component 1 K02746; COG: COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: eci:UTI89_C3571 3.2e-48 agaD; PTS system, N-acetylgalactosamine-specific IID component K02747; COG: COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; Psort location: CytoplasmicMembrane, score: 10.00. | 0.999 |
| EDS75656.1 | EDS75662.1 | CLOSPI_00166 | CLOSPI_00172 | KEGG: eci:UTI89_C3570 8.0e-36 agaC; PTS system, N-acetylgalactosamine-specific IIC component 1 K02746; COG: COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; Psort location: CytoplasmicMembrane, score: 10.00. | Sugar isomerase, AgaS family; KEGG: ppr:PBPRB0142 1.4e-84 putative phosphosugar isomerase K02082; COG: COG2222 Predicted phosphosugar isomerases; Psort location: Cytoplasmic, score: 8.87. | 0.789 |
| EDS75656.1 | EDS75665.1 | CLOSPI_00166 | CLOSPI_00175 | KEGG: eci:UTI89_C3570 8.0e-36 agaC; PTS system, N-acetylgalactosamine-specific IIC component 1 K02746; COG: COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; Psort location: CytoplasmicMembrane, score: 10.00. | Tagatose-6-phosphate kinase; KEGG: yps:YPTB3076 9.3e-97 agaZ; putative tagatose 6-phosphate kinase K00917; COG: COG4573 Predicted tagatose 6-phosphate kinase. | 0.745 |
| EDS75656.1 | EDS75675.1 | CLOSPI_00166 | CLOSPI_00185 | KEGG: eci:UTI89_C3570 8.0e-36 agaC; PTS system, N-acetylgalactosamine-specific IIC component 1 K02746; COG: COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; Psort location: CytoplasmicMembrane, score: 10.00. | Transcriptional regulator, AraC family; KEGG: bli:BL05281 2.5e-09 adaA; methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC/XylS family) K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: Cytoplasmic, score: 9.98. | 0.669 |
| EDS75657.1 | EDS75656.1 | CLOSPI_00167 | CLOSPI_00166 | KEGG: eci:UTI89_C3571 3.2e-48 agaD; PTS system, N-acetylgalactosamine-specific IID component K02747; COG: COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: eci:UTI89_C3570 8.0e-36 agaC; PTS system, N-acetylgalactosamine-specific IIC component 1 K02746; COG: COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; Psort location: CytoplasmicMembrane, score: 10.00. | 0.999 |
| EDS75657.1 | EDS75662.1 | CLOSPI_00167 | CLOSPI_00172 | KEGG: eci:UTI89_C3571 3.2e-48 agaD; PTS system, N-acetylgalactosamine-specific IID component K02747; COG: COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; Psort location: CytoplasmicMembrane, score: 10.00. | Sugar isomerase, AgaS family; KEGG: ppr:PBPRB0142 1.4e-84 putative phosphosugar isomerase K02082; COG: COG2222 Predicted phosphosugar isomerases; Psort location: Cytoplasmic, score: 8.87. | 0.777 |
| EDS75657.1 | EDS75665.1 | CLOSPI_00167 | CLOSPI_00175 | KEGG: eci:UTI89_C3571 3.2e-48 agaD; PTS system, N-acetylgalactosamine-specific IID component K02747; COG: COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; Psort location: CytoplasmicMembrane, score: 10.00. | Tagatose-6-phosphate kinase; KEGG: yps:YPTB3076 9.3e-97 agaZ; putative tagatose 6-phosphate kinase K00917; COG: COG4573 Predicted tagatose 6-phosphate kinase. | 0.757 |
| EDS75657.1 | EDS75675.1 | CLOSPI_00167 | CLOSPI_00185 | KEGG: eci:UTI89_C3571 3.2e-48 agaD; PTS system, N-acetylgalactosamine-specific IID component K02747; COG: COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; Psort location: CytoplasmicMembrane, score: 10.00. | Transcriptional regulator, AraC family; KEGG: bli:BL05281 2.5e-09 adaA; methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC/XylS family) K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: Cytoplasmic, score: 9.98. | 0.582 |
| EDS75662.1 | EDS74054.1 | CLOSPI_00172 | CLOSPI_02480 | Sugar isomerase, AgaS family; KEGG: ppr:PBPRB0142 1.4e-84 putative phosphosugar isomerase K02082; COG: COG2222 Predicted phosphosugar isomerases; Psort location: Cytoplasmic, score: 8.87. | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | 0.901 |
| EDS75662.1 | EDS75656.1 | CLOSPI_00172 | CLOSPI_00166 | Sugar isomerase, AgaS family; KEGG: ppr:PBPRB0142 1.4e-84 putative phosphosugar isomerase K02082; COG: COG2222 Predicted phosphosugar isomerases; Psort location: Cytoplasmic, score: 8.87. | KEGG: eci:UTI89_C3570 8.0e-36 agaC; PTS system, N-acetylgalactosamine-specific IIC component 1 K02746; COG: COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; Psort location: CytoplasmicMembrane, score: 10.00. | 0.789 |
| EDS75662.1 | EDS75657.1 | CLOSPI_00172 | CLOSPI_00167 | Sugar isomerase, AgaS family; KEGG: ppr:PBPRB0142 1.4e-84 putative phosphosugar isomerase K02082; COG: COG2222 Predicted phosphosugar isomerases; Psort location: Cytoplasmic, score: 8.87. | KEGG: eci:UTI89_C3571 3.2e-48 agaD; PTS system, N-acetylgalactosamine-specific IID component K02747; COG: COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; Psort location: CytoplasmicMembrane, score: 10.00. | 0.777 |
| EDS75662.1 | EDS75665.1 | CLOSPI_00172 | CLOSPI_00175 | Sugar isomerase, AgaS family; KEGG: ppr:PBPRB0142 1.4e-84 putative phosphosugar isomerase K02082; COG: COG2222 Predicted phosphosugar isomerases; Psort location: Cytoplasmic, score: 8.87. | Tagatose-6-phosphate kinase; KEGG: yps:YPTB3076 9.3e-97 agaZ; putative tagatose 6-phosphate kinase K00917; COG: COG4573 Predicted tagatose 6-phosphate kinase. | 0.808 |
| EDS75662.1 | EDS75675.1 | CLOSPI_00172 | CLOSPI_00185 | Sugar isomerase, AgaS family; KEGG: ppr:PBPRB0142 1.4e-84 putative phosphosugar isomerase K02082; COG: COG2222 Predicted phosphosugar isomerases; Psort location: Cytoplasmic, score: 8.87. | Transcriptional regulator, AraC family; KEGG: bli:BL05281 2.5e-09 adaA; methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC/XylS family) K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: Cytoplasmic, score: 9.98. | 0.703 |