STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75677.1Transcriptional regulator, AsnC family; COG: COG1522 Transcriptional regulators; Psort location: Cytoplasmic, score: 8.87. (163 aa)    
Predicted Functional Partners:
EDS75678.1
Aminotransferase, class I/II; KEGG: cpe:CPE0711 9.7e-118 aspC; aspartate aminotransferase; COG: COG0436 Aspartate/tyrosine/aromatic aminotransferase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.952
nifJ
KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
    
 0.913
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
 
 0.849
EDS75491.1
Hypothetical protein; KEGG: sha:SH0521 2.0e-10 ptsG; phosphotransferase system enzyme II K02777:K02778:K02779; COG: COG2190 Phosphotransferase system IIA components.
   
 
  0.818
EDS73779.1
KEGG: sar:SAR0235 1.9e-137 putative PTS transport system, IIBC component K02790:K02791; COG: COG1264 Phosphotransferase system IIB components; Psort location: CytoplasmicMembrane, score: 10.00.
   
 
  0.818
EDS75817.1
Class II glutamine amidotransferase; KEGG: syn:sll1502 0. gltB; NADH-dependent glutamate synthase large subunit K00268; COG: COG0069 Glutamate synthase domain 2; Psort location: Cytoplasmic, score: 8.87.
     
 0.523
ilvB
KEGG: chy:CHY_0517 2.1e-163 ilvB1; acetolactate synthase, large subunit, biosynthetic type K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.486
ilvE
Branched-chain-amino-acid transaminase; KEGG: bha:BH2156 1.6e-110 bcaT; branched-chain amino acid aminotransferase K00826; COG: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; Psort location: Cytoplasmic, score: 8.87.
    
 0.485
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
    
 0.457
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
    
 0.457
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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