STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75701.1ThiF family protein; KEGG: cal:orf19.2115 1.9e-25 molybdopterin-converting factor; COG: COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; Psort location: Cytoplasmic, score: 8.87. (228 aa)    
Predicted Functional Partners:
EDS75702.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.773
EDS75703.1
Hypothetical protein; KEGG: mpn:MPN473 2.3e-07 lip2, P01_orf268; triacylglycerol lipase (lip) 2; COG: COG1073 Hydrolases of the alpha/beta superfamily; Psort location: Cytoplasmic, score: 8.87.
       0.773
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
    
 0.737
EDS74769.1
ThiF family protein; KEGG: cps:CPS_4642 2.2e-08 thiF; adenylyltransferase ThiF K03148; COG: COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
 
 0.706
miaA
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
      0.702
EDS75128.1
Aminotransferase, class V; KEGG: oih:OB2199 9.8e-86 L-cysteine sulfurtransferase (iron-sulfur cofactor synthesis) K04487; COG: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; Psort location: Cytoplasmic, score: 8.87.
    
 0.640
EDS74574.1
FAD dependent oxidoreductase; KEGG: mma:MM1656 1.6e-55 oxidoreductase K00100; COG: COG0665 Glycine/D-amino acid oxidases (deaminating); Psort location: Cytoplasmic, score: 8.87.
    
  0.611
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
     
 0.590
EDS74770.1
Hypothetical protein; COG: NOG38277 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
 0.557
EDS75700.1
DNA-binding helix-turn-helix protein; KEGG: sco:SCO5998 0.00038 murA2, SCBAC1C11.01c, StBAC16H6.33c; putative UDP-N-acetylglucosamine transferase K00790; COG: COG1396 Predicted transcriptional regulators.
       0.533
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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