STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75741.1Radical SAM domain protein; KEGG: bha:BH2952 1.3e-104 Mg-protoporphyrin IX monomethyl ester oxidative cyclase K04034; COG: COG1032 Fe-S oxidoreductase; Psort location: Cytoplasmic, score: 8.87. (544 aa)    
Predicted Functional Partners:
EDS75249.1
Radical SAM protein, TIGR01212 family; KEGG: btk:BT9727_4481 2.2e-88 conserved hypothetical protein, possible Fe-S oxidoreductase; COG: COG1242 Predicted Fe-S oxidoreductase; Psort location: Cytoplasmic, score: 8.87.
   
 0.696
rdgB
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
      0.650
EDS75740.1
Serine-type D-Ala-D-Ala carboxypeptidase; KEGG: oih:OB0530 5.6e-39 carboxypeptidase K07260; COG: COG1876 D-alanyl-D-alanine carboxypeptidase; Psort location: Cytoplasmic, score: 9.36.
       0.615
EDS75738.1
Hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type; KEGG: ctc:CTC02562 9.2e-90 fumarate hydratase subunit A K01677; COG: COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Psort location: Cytoplasmic, score: 8.87.
       0.577
EDS75739.1
Hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type; KEGG: ctc:CTC02561 1.1e-56 fumarate hydratase subunit B K01678; COG: COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain; Psort location: Cytoplasmic, score: 8.87.
       0.577
nrdD
KEGG: pac:PPA2137 8.7e-236 anaerobic ribonucleoside triphosphate reductase K00527; COG: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score: 8.87.
       0.509
nrdG
Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
       0.509
EDS73707.1
KEGG: ret:RHE_PB00012 1.5e-80 probable ABC transporter, ATP-binding protein K06022; COG: COG0488 ATPase components of ABC transporters with duplicated ATPase domains; Psort location: CytoplasmicMembrane, score: 9.49.
  
     0.439
EDS74098.1
Methyltransferase small domain protein; KEGG: btl:BALH_0099 5.4e-46 16S rRNA m(2)G 1207 methyltransferase K00564; COG: COG2813 16S RNA G1207 methylase RsmC; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.438
sasPA
Small, acid-soluble spore protein A; COG: NOG16862 non supervised orthologous group; Psort location: Extracellular, score: 8.82.
  
     0.425
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.