STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75819.1ImpB/MucB/SamB family protein; KEGG: btl:BALH_p0040 1.5e-41 uvrX; DNA-damage repair protein (DNA polymerase IV) K00961; COG: COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; Psort location: Cytoplasmic, score: 8.87. (506 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.985
EDS75820.1
YolD-like protein.
 
    0.953
nifJ
KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.945
EDS75872.1
DNA-binding helix-turn-helix protein; KEGG: chy:CHY_1378 5.1e-18 lexA; LexA repressor K01356; COG: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); Psort location: Cytoplasmic, score: 8.87.
  
 
 0.757
EDS75763.1
Hypothetical protein; KEGG: pub:SAR11_0453 8.8e-05 aroK; shikimate kinase K00891.
     
 0.751
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.745
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.742
EDS75418.1
Hypothetical protein.
  
 
 0.673
EDS75490.1
Cell cycle protein, FtsW/RodA/SpoVE family; COG: COG0772 Bacterial cell division membrane protein; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family.
  
 
 0.606
EDS74134.1
Cell cycle protein, FtsW/RodA/SpoVE family; COG: COG0772 Bacterial cell division membrane protein; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family.
  
 
 0.606
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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