STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75838.1Bacterial peptidase A24, N-terminal domain protein; KEGG: ctc:CTC02411 1.1e-36 pilD; type IV prepilin leader peptidase pilD K02654; COG: COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; Psort location: CytoplasmicMembrane, score: 10.00. (233 aa)    
Predicted Functional Partners:
EDS74964.1
KEGG: pen:PSEEN2333 1.1e-38 xcpR-2; type II secretion pathway protein E K01509; COG: COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; Psort location: Cytoplasmic, score: 9.36.
 
 
 0.890
EDS75475.1
DNA internalization competence protein ComEC/Rec2-like protein; KEGG: cel:ND6 0.00029 NADH dehydrogenase subunit 6 K03884; COG: COG0658 Predicted membrane metal-binding protein; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.836
EDS74962.1
Prepilin-type cleavage/methylation N-terminal domain protein; COG: COG4537 Competence protein ComGC.
 
  
 0.690
dprA
DNA protecting protein DprA; COG: COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.
 
  
 0.665
EDS75476.1
COG: COG1555 DNA uptake protein and related DNA-binding proteins; Psort location: Cytoplasmic, score: 8.87.
   
  
 0.655
EDS74963.1
Bacterial type II secretion system domain protein F; COG: COG1459 Type II secretory pathway, component PulF; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.625
EDS76042.1
Hypothetical protein; COG: COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.613
EDS75837.1
Sodium:neurotransmitter symporter family protein; KEGG: smu:SMU.1017 0.00063 oadB; putative oxaloacetate decarboxylase, sodium ion pump subunit K01572; COG: COG0733 Na+-dependent transporters of the SNF family; Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
       0.505
lepB
KEGG: bce:BC3837 2.5e-32 signal peptidase I K03100; COG: COG0681 Signal peptidase I; Belongs to the peptidase S26 family.
 
   
 0.464
comFA
ComF operon protein 1; KEGG: erw:ERWE_CDS_00310 4.1e-09 recG; ATP-dependent DNA helicase RecG K03655; COG: COG4098 Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein).
   
  
 0.460
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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