| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDS74951.1 | EDS75848.1 | CLOSPI_01266 | CLOSPI_00378 | Polyprenyl synthetase; KEGG: cac:CAC2080 2.9e-61 predicted geranylgeranyl pyrophosphate synthase K00795; COG: COG0142 Geranylgeranyl pyrophosphate synthase; Psort location: Cytoplasmic, score: 9.65; Belongs to the FPP/GGPP synthase family. | Putative rRNA methylase; KEGG: spb:M28_Spy0305 9.0e-28 SAM-dependent methyltransferase; COG: COG0500 SAM-dependent methyltransferases. | 0.644 |
| EDS75249.1 | EDS75848.1 | CLOSPI_01094 | CLOSPI_00378 | Radical SAM protein, TIGR01212 family; KEGG: btk:BT9727_4481 2.2e-88 conserved hypothetical protein, possible Fe-S oxidoreductase; COG: COG1242 Predicted Fe-S oxidoreductase; Psort location: Cytoplasmic, score: 8.87. | Putative rRNA methylase; KEGG: spb:M28_Spy0305 9.0e-28 SAM-dependent methyltransferase; COG: COG0500 SAM-dependent methyltransferases. | 0.919 |
| EDS75848.1 | EDS74951.1 | CLOSPI_00378 | CLOSPI_01266 | Putative rRNA methylase; KEGG: spb:M28_Spy0305 9.0e-28 SAM-dependent methyltransferase; COG: COG0500 SAM-dependent methyltransferases. | Polyprenyl synthetase; KEGG: cac:CAC2080 2.9e-61 predicted geranylgeranyl pyrophosphate synthase K00795; COG: COG0142 Geranylgeranyl pyrophosphate synthase; Psort location: Cytoplasmic, score: 9.65; Belongs to the FPP/GGPP synthase family. | 0.644 |
| EDS75848.1 | EDS75249.1 | CLOSPI_00378 | CLOSPI_01094 | Putative rRNA methylase; KEGG: spb:M28_Spy0305 9.0e-28 SAM-dependent methyltransferase; COG: COG0500 SAM-dependent methyltransferases. | Radical SAM protein, TIGR01212 family; KEGG: btk:BT9727_4481 2.2e-88 conserved hypothetical protein, possible Fe-S oxidoreductase; COG: COG1242 Predicted Fe-S oxidoreductase; Psort location: Cytoplasmic, score: 8.87. | 0.919 |
| EDS75848.1 | EDS75851.1 | CLOSPI_00378 | CLOSPI_00381 | Putative rRNA methylase; KEGG: spb:M28_Spy0305 9.0e-28 SAM-dependent methyltransferase; COG: COG0500 SAM-dependent methyltransferases. | Site-specific recombinase, phage integrase family; COG: COG4974 Site-specific recombinase XerD; Belongs to the 'phage' integrase family. | 0.404 |
| EDS75848.1 | bioB | CLOSPI_00378 | CLOSPI_00380 | Putative rRNA methylase; KEGG: spb:M28_Spy0305 9.0e-28 SAM-dependent methyltransferase; COG: COG0500 SAM-dependent methyltransferases. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.815 |
| EDS75848.1 | bioD | CLOSPI_00378 | CLOSPI_00379 | Putative rRNA methylase; KEGG: spb:M28_Spy0305 9.0e-28 SAM-dependent methyltransferase; COG: COG0500 SAM-dependent methyltransferases. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.810 |
| EDS75848.1 | nifJ | CLOSPI_00378 | CLOSPI_00003 | Putative rRNA methylase; KEGG: spb:M28_Spy0305 9.0e-28 SAM-dependent methyltransferase; COG: COG0500 SAM-dependent methyltransferases. | KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87. | 0.466 |
| EDS75851.1 | EDS75848.1 | CLOSPI_00381 | CLOSPI_00378 | Site-specific recombinase, phage integrase family; COG: COG4974 Site-specific recombinase XerD; Belongs to the 'phage' integrase family. | Putative rRNA methylase; KEGG: spb:M28_Spy0305 9.0e-28 SAM-dependent methyltransferase; COG: COG0500 SAM-dependent methyltransferases. | 0.404 |
| EDS75851.1 | bioB | CLOSPI_00381 | CLOSPI_00380 | Site-specific recombinase, phage integrase family; COG: COG4974 Site-specific recombinase XerD; Belongs to the 'phage' integrase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.404 |
| EDS75851.1 | bioD | CLOSPI_00381 | CLOSPI_00379 | Site-specific recombinase, phage integrase family; COG: COG4974 Site-specific recombinase XerD; Belongs to the 'phage' integrase family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.404 |
| bioB | EDS75848.1 | CLOSPI_00380 | CLOSPI_00378 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Putative rRNA methylase; KEGG: spb:M28_Spy0305 9.0e-28 SAM-dependent methyltransferase; COG: COG0500 SAM-dependent methyltransferases. | 0.815 |
| bioB | EDS75851.1 | CLOSPI_00380 | CLOSPI_00381 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Site-specific recombinase, phage integrase family; COG: COG4974 Site-specific recombinase XerD; Belongs to the 'phage' integrase family. | 0.404 |
| bioB | bioD | CLOSPI_00380 | CLOSPI_00379 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.999 |
| bioD | EDS75848.1 | CLOSPI_00379 | CLOSPI_00378 | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Putative rRNA methylase; KEGG: spb:M28_Spy0305 9.0e-28 SAM-dependent methyltransferase; COG: COG0500 SAM-dependent methyltransferases. | 0.810 |
| bioD | EDS75851.1 | CLOSPI_00379 | CLOSPI_00381 | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Site-specific recombinase, phage integrase family; COG: COG4974 Site-specific recombinase XerD; Belongs to the 'phage' integrase family. | 0.404 |
| bioD | bioB | CLOSPI_00379 | CLOSPI_00380 | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.999 |
| nifJ | EDS75848.1 | CLOSPI_00003 | CLOSPI_00378 | KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87. | Putative rRNA methylase; KEGG: spb:M28_Spy0305 9.0e-28 SAM-dependent methyltransferase; COG: COG0500 SAM-dependent methyltransferases. | 0.466 |