STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (319 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 0.996
argD
Aminotransferase, acetylornithine/succinylornithine family; KEGG: mja:MJ0721 3.6e-95 argD; acetylornithine aminotransferase K00818; COG: COG4992 Ornithine/acetylornithine aminotransferase; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.950
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
 
 0.921
EDS75848.1
Putative rRNA methylase; KEGG: spb:M28_Spy0305 9.0e-28 SAM-dependent methyltransferase; COG: COG0500 SAM-dependent methyltransferases.
  
 
 0.844
EDS74435.1
VanZ-like protein; COG: COG4767 Glycopeptide antibiotics resistance protein; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.648
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
    
 0.475
EDS74444.1
Hydrogenase, Fe-only; KEGG: tte:TTE0894 1.4e-180 nuoG; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) K00336; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.464
EDS74098.1
Methyltransferase small domain protein; KEGG: btl:BALH_0099 5.4e-46 16S rRNA m(2)G 1207 methyltransferase K00564; COG: COG2813 16S RNA G1207 methylase RsmC; Psort location: Cytoplasmic, score: 8.87.
    
  0.437
LYS1
KEGG: spd:SPD_0812 4.2e-165 lys1; saccharopine dehydrogenase K00290; COG: COG1748 Saccharopine dehydrogenase and related proteins; Psort location: Cytoplasmic, score: 8.87.
   
 
  0.436
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.434
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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