STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75872.1DNA-binding helix-turn-helix protein; KEGG: chy:CHY_1378 5.1e-18 lexA; LexA repressor K01356; COG: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); Psort location: Cytoplasmic, score: 8.87. (206 aa)    
Predicted Functional Partners:
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.978
EDS75819.1
ImpB/MucB/SamB family protein; KEGG: btl:BALH_p0040 1.5e-41 uvrX; DNA-damage repair protein (DNA polymerase IV) K00961; COG: COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.757
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
 
 0.757
EDS74144.1
UvrD/REP helicase; KEGG: mmo:MMOB4890 1.4e-141 pcrA1; ATP-dependent DNA helicase K03657; COG: COG0210 Superfamily I DNA and RNA helicases; Psort location: Cytoplasmic, score: 8.87.
    
 0.671
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.657
EDS75873.1
Hypothetical protein; Psort location: Extracellular, score: 8.82.
       0.512
EDS75874.1
Hypothetical protein; Psort location: Extracellular, score: 8.82.
       0.512
recX
Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family.
  
  
 0.448
EDS73788.1
Transcriptional regulator, AraC family; KEGG: bsu:BG10166 1.7e-13 adaA; methylphosphotriester-DNA alkyltransferase / transcriptional regulator (AraC family) K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: Cytoplasmic, score: 9.65.
   
   0.439
EDS73791.1
KEGG: bcz:BCZK3497 2.1e-12 adaA; transcriptional regulator, AraC family K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: Cytoplasmic, score: 9.98.
   
   0.439
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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