Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDS75890.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. (250 aa)    
Predicted Functional Partners:
EDS75889.1
Putative diadenosine tetraphosphatase; KEGG: ban:BA0570 6.3e-27 serine/threonine phosphatase, putative K07313; COG: COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; Psort location: Cytoplasmic, score: 8.87.
  
    0.776
fnt
KEGG: psp:PSPPH_4690 1.6e-23 formate transporter K00122; COG: COG2116 Formate/nitrite family of transporters; Psort location: CytoplasmicMembrane, score: 9.99.
       0.615
EDS75491.1
Hypothetical protein; KEGG: sha:SH0521 2.0e-10 ptsG; phosphotransferase system enzyme II K02777:K02778:K02779; COG: COG2190 Phosphotransferase system IIA components.
  
  
 0.568
EDS73779.1
KEGG: sar:SAR0235 1.9e-137 putative PTS transport system, IIBC component K02790:K02791; COG: COG1264 Phosphotransferase system IIB components; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.568
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
       0.410
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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