STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDS75891.1KEGG: bcz:BCZK5094 1.5e-25 hydrolase, haloacid dehalogenase-like family K01564; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87. (271 aa)    
Predicted Functional Partners:
EDS75903.1
KEGG: sak:SAK_0393 2.1e-19 Cof-like hydrolase/peptidyl-prolyl cis-trans isomerase domain protein; COG: COG0561 Predicted hydrolases of the HAD superfamily.
  
     0.772
EDS74993.1
Cof-like hydrolase; KEGG: spz:M5005_Spy_1331 1.6e-18 peptidyl-prolyl cis-trans isomerase K01802; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87.
     0.746
EDS75583.1
HAD hydrolase, family IIB; KEGG: sak:SAK_0393 1.9e-15 Cof-like hydrolase/peptidyl-prolyl cis-trans isomerase domain protein; COG: COG0561 Predicted hydrolases of the HAD superfamily.
 
     0.697
EDS75893.1
Hypothetical protein.
       0.554
EDS74966.1
PHP domain protein; KEGG: reh:H16_A1200 1.8e-20 predicted metal-dependent phosphoesterase (PHP family); COG: COG0613 Predicted metal-dependent phosphoesterases (PHP family); Psort location: Cytoplasmic, score: 8.87.
 
      0.456
EDS75895.1
Putative RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
       0.428
EDS75892.1
Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.422
rdgB
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.422
EDS75896.1
TIGR01906 family protein; COG: COG4478 Predicted membrane protein; Psort location: CytoplasmicMembrane, score: 9.99.
       0.422
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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