| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDS74169.1 | EDS75895.1 | CLOSPI_01751 | CLOSPI_00425 | COG: COG3619 Predicted membrane protein; Psort location: CytoplasmicMembrane, score: 9.99. | Putative RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | 0.712 |
| EDS74574.1 | EDS75895.1 | CLOSPI_01629 | CLOSPI_00425 | FAD dependent oxidoreductase; KEGG: mma:MM1656 1.6e-55 oxidoreductase K00100; COG: COG0665 Glycine/D-amino acid oxidases (deaminating); Psort location: Cytoplasmic, score: 8.87. | Putative RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | 0.562 |
| EDS75892.1 | EDS75893.1 | CLOSPI_00422 | CLOSPI_00423 | Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Hypothetical protein. | 0.572 |
| EDS75892.1 | EDS75895.1 | CLOSPI_00422 | CLOSPI_00425 | Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Putative RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | 0.785 |
| EDS75892.1 | EDS75896.1 | CLOSPI_00422 | CLOSPI_00426 | Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | TIGR01906 family protein; COG: COG4478 Predicted membrane protein; Psort location: CytoplasmicMembrane, score: 9.99. | 0.775 |
| EDS75892.1 | rdgB | CLOSPI_00422 | CLOSPI_00424 | Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.804 |
| EDS75892.1 | sun | CLOSPI_00422 | CLOSPI_00554 | Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.564 |
| EDS75893.1 | EDS75892.1 | CLOSPI_00423 | CLOSPI_00422 | Hypothetical protein. | Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.572 |
| EDS75893.1 | EDS75895.1 | CLOSPI_00423 | CLOSPI_00425 | Hypothetical protein. | Putative RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | 0.572 |
| EDS75893.1 | EDS75896.1 | CLOSPI_00423 | CLOSPI_00426 | Hypothetical protein. | TIGR01906 family protein; COG: COG4478 Predicted membrane protein; Psort location: CytoplasmicMembrane, score: 9.99. | 0.572 |
| EDS75893.1 | rdgB | CLOSPI_00423 | CLOSPI_00424 | Hypothetical protein. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.572 |
| EDS75895.1 | EDS74169.1 | CLOSPI_00425 | CLOSPI_01751 | Putative RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | COG: COG3619 Predicted membrane protein; Psort location: CytoplasmicMembrane, score: 9.99. | 0.712 |
| EDS75895.1 | EDS74574.1 | CLOSPI_00425 | CLOSPI_01629 | Putative RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | FAD dependent oxidoreductase; KEGG: mma:MM1656 1.6e-55 oxidoreductase K00100; COG: COG0665 Glycine/D-amino acid oxidases (deaminating); Psort location: Cytoplasmic, score: 8.87. | 0.562 |
| EDS75895.1 | EDS75892.1 | CLOSPI_00425 | CLOSPI_00422 | Putative RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.785 |
| EDS75895.1 | EDS75893.1 | CLOSPI_00425 | CLOSPI_00423 | Putative RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | Hypothetical protein. | 0.572 |
| EDS75895.1 | EDS75896.1 | CLOSPI_00425 | CLOSPI_00426 | Putative RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | TIGR01906 family protein; COG: COG4478 Predicted membrane protein; Psort location: CytoplasmicMembrane, score: 9.99. | 0.795 |
| EDS75895.1 | nnrD | CLOSPI_00425 | CLOSPI_00545 | Putative RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | YjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.457 |
| EDS75895.1 | rdgB | CLOSPI_00425 | CLOSPI_00424 | Putative RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.829 |
| EDS75895.1 | rlmH | CLOSPI_00425 | CLOSPI_02200 | Putative RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.458 |
| EDS75895.1 | sun | CLOSPI_00425 | CLOSPI_00554 | Putative RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.479 |
