STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75937.1Aminotransferase, class I/II; KEGG: mmp:MMP0096 9.6e-79 aminotransferase (subgroup I); COG: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; Psort location: Cytoplasmic, score: 9.98. (412 aa)    
Predicted Functional Partners:
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.905
EDS75817.1
Class II glutamine amidotransferase; KEGG: syn:sll1502 0. gltB; NADH-dependent glutamate synthase large subunit K00268; COG: COG0069 Glutamate synthase domain 2; Psort location: Cytoplasmic, score: 8.87.
  
 
  0.902
EDS74665.1
Glutamine synthetase, beta-grasp domain protein; KEGG: mma:MM0964 3.0e-91 glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: Cytoplasmic, score: 9.98.
    
 0.901
glnA
Glutamate--ammonia ligase, catalytic domain protein; KEGG: tte:TTE0821 2.5e-229 glnA; Glutamine synthase K01915; COG: COG3968 Uncharacterized protein related to glutamine synthetase; Psort location: Cytoplasmic, score: 9.65.
     
  0.900
glnA-2
Glutamate--ammonia ligase, catalytic domain protein; KEGG: tte:TTE0821 1.3e-200 glnA; Glutamine synthase K01915; COG: COG3968 Uncharacterized protein related to glutamine synthetase; Psort location: Cytoplasmic, score: 9.98.
     
  0.900
EDS75938.1
Putative phage DNA packaging protein; COG: COG1376 Uncharacterized protein conserved in bacteria.
       0.553
EDS75936.1
Hypothetical protein; KEGG: tte:TTE1261 0.0040 aroE; shikimate 5-dehydrogenase K00014; Psort location: Cytoplasmic, score: 8.87.
  
    0.548
EDS74223.1
4Fe-4S binding domain protein; KEGG: mka:MK0930 1.7e-05 coenzyme F420-reducing hydrogenase, gamma subunit K00439; COG: COG1145 Ferredoxin; Psort location: Cytoplasmic, score: 8.87.
    
   0.453
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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