STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75487.1Adenylate cyclase; KEGG: sar:SAR0971 6.8e-23 glutathione S-transferase K00799; COG: COG4116 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. (191 aa)    
Predicted Functional Partners:
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
     0.714
recU
Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
  
     0.692
EDS75486.1
Transcriptional regulator, Spx/MgsR family; KEGG: lsl:LSL_1330 9.1e-35 arsC; arsenate reductase; COG: COG1393 Arsenate reductase and related proteins, glutaredoxin family; Psort location: Cytoplasmic, score: 8.87; Belongs to the ArsC family.
  
     0.684
EDS74962.1
Prepilin-type cleavage/methylation N-terminal domain protein; COG: COG4537 Competence protein ComGC.
  
     0.646
EDS74803.1
DivIVA domain protein; KEGG: lwe:lwe2040 6.2e-06 cell division protein DivIVA K01549; COG: COG3599 Cell division initiation protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.622
EDS75003.1
Penicillin-binding protein, transpeptidase domain protein; KEGG: bcz:BCZK2246 1.8e-93 pbp2; penicillin-binding protein 2 K05364; COG: COG0768 Cell division protein FtsI/penicillin-binding protein 2; Psort location: CytoplasmicMembrane, score: 9.82.
  
     0.613
nadK
NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.609
EDS75489.1
Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
       0.603
EDS75129.1
Putative septation ring formation regulator EzrA; KEGG: fnu:FN0522 3.9e-11 exonuclease SBCC K03546; COG: COG4477 Negative regulator of septation ring formation; Psort location: Cytoplasmic, score: 8.87.
  
     0.602
EDS76029.1
KEGG: sph:MGAS10270_Spy0282 3.5e-05 dnaB; replicative DNA helicase K01529; COG: COG3611 Replication initiation/membrane attachment protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.588
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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