STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKNAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (260 aa)    
Predicted Functional Partners:
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.927
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.913
EDS75489.1
Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
  
  
 0.801
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
    
 0.653
EDS75995.1
Transcriptional regulator, Sir2 family; KEGG: tte:TTE1570 7.9e-13 sir2; NAD-dependent protein deacetylase, Sir2 family K01463; COG: COG0846 NAD-dependent protein deacetylases, SIR2 family; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.644
EDS74970.1
Amino acid permease; KEGG: eci:UTI89_C0120 1.6e-06 aroP; aromatic amino acid transport protein AroP K03293; COG: COG0531 Amino acid transporters; Psort location: CytoplasmicMembrane, score: 9.99.
   
 
 0.638
EDS75415.1
Hydrolase, NUDIX family; KEGG: bsu:BG11762 8.0e-36 nudF, yqkG; ADP-ribose pyrophosphatase K01515; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: Cytoplasmic, score: 8.87.
    
 0.611
EDS75487.1
Adenylate cyclase; KEGG: sar:SAR0971 6.8e-23 glutathione S-transferase K00799; COG: COG4116 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
       0.609
EDS75366.1
Hypothetical protein.
     
 0.596
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
    
 0.595
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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