Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDS75507.1NlpC/P60 family protein; KEGG: bcz:BCZK2310 2.2e-18 bacillolysin K01400; COG: COG0791 Cell wall-associated hydrolases (invasion-associated proteins); Psort location: Extracellular, score: 9.55. (481 aa)    
Predicted Functional Partners:
ftsX
Cell division protein FtsX; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
 
 0.710
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
 
 
 0.568
EDS73879.1
Peptidase, S41 family; KEGG: gka:GK3092 7.3e-65 carboxyl-terminal processing protease; COG: COG0793 Periplasmic protease; Belongs to the peptidase S41A family.
   
 
 0.559
nnrD
YjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
  
    0.550
EDS75505.1
KEGG: fal:FRAAL5379 7.6e-47 ABC transporter ATP-binding protein K06020; COG: COG1136 ABC-type antimicrobial peptide transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
   
   0.463
EDS75506.1
Efflux ABC transporter, permease protein; KEGG: cal:orf19.2410 6.5e-06 IMH1; involved in vesicular transport K01553; COG: COG0577 ABC-type antimicrobial peptide transport system, permease component; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.450
EDS75230.1
LysM domain protein; KEGG: aeh:Mlg_1995 5.1e-06 lytic transglycosylase, catalytic K08307; COG: COG3409 Putative peptidoglycan-binding domain-containing protein.
  
 
 0.443
EDS73734.1
NlpC/P60 family protein; KEGG: bce:BC5234 4.2e-09 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG0791 Cell wall-associated hydrolases (invasion-associated proteins); Psort location: Extracellular, score: 9.55.
 
  
0.419
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
 
   
 0.416
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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