STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
nnrDYjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] (494 aa)    
Predicted Functional Partners:
EDS75415.1
Hydrolase, NUDIX family; KEGG: bsu:BG11762 8.0e-36 nudF, yqkG; ADP-ribose pyrophosphatase K01515; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: Cytoplasmic, score: 8.87.
  
 0.968
EDS76046.1
DEAD/DEAH box helicase; KEGG: sab:SAB1965c 4.8e-93 ATP-dependent RNA helicase; COG: COG0513 Superfamily II DNA and RNA helicases; Psort location: Cytoplasmic, score: 8.87; Belongs to the DEAD box helicase family.
  
 0.896
EDS74286.1
DEAD/DEAH box helicase; KEGG: sab:SAB1430c 5.4e-101 probable ATP-dependent RNA helicase K01529; COG: COG0513 Superfamily II DNA and RNA helicases; Psort location: Cytoplasmic, score: 8.87.
  
 0.896
EDS74173.1
Hydrolase, P-loop family; KEGG: cjk:jk1734 2.1e-14 alr; hypothetical protein K01775; COG: COG0802 Predicted ATPase or kinase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.750
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
   0.727
nifJ
KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
   0.680
glgP
Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
   0.671
EDS74445.1
4Fe-4S binding domain protein; KEGG: tte:TTE0893 7.2e-225 nuoF; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit K00335; COG: COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; Psort location: Cytoplasmic, score: 9.98.
  
   0.647
EDS74122.1
Tex-like protein N-terminal domain protein; KEGG: ava:Ava_1534 1.3e-147 RNA binding S1; COG: COG2183 Transcriptional accessory protein; Psort location: Cytoplasmic, score: 8.87.
   
   0.628
EDS76037.1
RNA methyltransferase, TrmH family; KEGG: btl:BALH_4143 8.7e-46 spoU; 23S rRNA methyltransferase K00556; COG: COG0566 rRNA methylases; Psort location: Cytoplasmic, score: 8.87; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
   
 
 0.603
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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