STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmN23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (342 aa)    
Predicted Functional Partners:
sun
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.970
EDS75520.1
Kinase domain protein; KEGG: lmo:lmo1820 5.3e-110 similar to putative serine/threonine-specific protein kinase K08884; COG: COG2815 Uncharacterized protein conserved in bacteria; Psort location: CytoplasmicMembrane, score: 9.49.
  
  
 0.863
EDS75519.1
Protein phosphatase 2C; KEGG: bsu:BG13390 1.1e-43 prpC, yloO; PP2C protein phosphatase K01090; COG: COG0631 Serine/threonine protein phosphatase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.851
rsgA
Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
  
  
 0.846
rpe
KEGG: mcp:MCAP_0260 5.8e-49 rpe; ribulose-phosphate 3-epimerase K01783; COG: COG0036 Pentose-5-phosphate-3-epimerase; Psort location: Cytoplasmic, score: 8.87.
  
    0.811
EDS75523.1
KEGG: cpf:CPF_1988 3.6e-24 thiamine pyrophosphokinase K00949; COG: COG1564 Thiamine pyrophosphokinase; Psort location: Cytoplasmic, score: 8.87.
       0.807
EDS75472.1
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
 
   
 0.723
EDS74211.1
NOL1/NOP2/sun family protein; KEGG: spa:M6_Spy0946 4.3e-76 putative 23S rRNA m(5)C methyltransferase K00599; COG: COG3270 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.699
miaB
tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
 
  
 0.606
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
    0.545
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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