STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75523.1KEGG: cpf:CPF_1988 3.6e-24 thiamine pyrophosphokinase K00949; COG: COG1564 Thiamine pyrophosphokinase; Psort location: Cytoplasmic, score: 8.87. (198 aa)    
Predicted Functional Partners:
rsgA
Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
  
 
 0.975
nifJ
KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
   
   0.898
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.855
sun
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
 
   
 0.841
rpe
KEGG: mcp:MCAP_0260 5.8e-49 rpe; ribulose-phosphate 3-epimerase K01783; COG: COG0036 Pentose-5-phosphate-3-epimerase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.829
EDS75520.1
Kinase domain protein; KEGG: lmo:lmo1820 5.3e-110 similar to putative serine/threonine-specific protein kinase K08884; COG: COG2815 Uncharacterized protein conserved in bacteria; Psort location: CytoplasmicMembrane, score: 9.49.
  
  
 0.824
EDS75519.1
Protein phosphatase 2C; KEGG: bsu:BG13390 1.1e-43 prpC, yloO; PP2C protein phosphatase K01090; COG: COG0631 Serine/threonine protein phosphatase; Psort location: Cytoplasmic, score: 8.87.
     
 0.823
rlmN
23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
       0.807
thiD
KEGG: cac:CAC3095 5.2e-80 thiK; phosphomethylpyrimidine kinase K00877:K00941; COG: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
    
 0.700
EDS74628.1
Glycerophosphodiester phosphodiesterase family protein; KEGG: cac:CAC0430 8.1e-43 glycerophosphoryl diester phosphodiesterase K01126; COG: COG0584 Glycerophosphoryl diester phosphodiesterase; Psort location: Cytoplasmic, score: 9.98.
  
  
  0.649
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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