STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75530.1HAD hydrolase, family IA, variant 3; KEGG: mpu:MYPU_6350 3.4e-12 pgmB; beta-phosphoglucomutase K01838; COG: COG0637 Predicted phosphatase/phosphohexomutase. (225 aa)    
Predicted Functional Partners:
thiD
KEGG: cac:CAC3095 5.2e-80 thiK; phosphomethylpyrimidine kinase K00877:K00941; COG: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
      0.968
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
      0.921
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
 
 
  0.855
thiM
Putative hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
       0.794
EDS75952.1
Hypothetical protein; KEGG: vfi:VFA0937 6.9e-14 phosphoglycolate phosphatase K01091; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: Cytoplasmic, score: 8.87.
  
     0.762
EDS75113.1
Molybdopterin binding domain protein; KEGG: mmu:319945 0.00014 Flad1; RFad1, flavin adenine dinucleotide synthetase, homolog (yeast) K00953; COG: COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Psort location: Cytoplasmic, score: 8.87.
    
  0.695
EDS74810.1
Competence/damage-inducible domain protein CinA; COG: COG1546 Uncharacterized protein (competence- and mitomycin-induced); Psort location: Cytoplasmic, score: 8.87; Belongs to the CinA family.
    
  0.695
EDS74902.1
Pseudouridylate synthase; KEGG: tte:TTE0052 1.1e-61 rsuA; 16S rRNA uridine-516 pseudouridylate synthase and related Pseudouridylate synthase K06183; COG: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Psort location: Cytoplasmic, score: 8.87; Belongs to the pseudouridine synthase RsuA family.
      0.652
EDS75659.1
Haloacid dehalogenase-like hydrolase; KEGG: cac:CAC2614 2.3e-15 beta-phosphoglucomutase K01838; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: Cytoplasmic, score: 8.87.
  
     0.561
EDS75803.1
PRD domain protein; KEGG: sph:MGAS10270_Spy1732 1.0e-25 transcription antiterminator, BglG family / PTS system, mannitol (cryptic)-specific IIA component K00890; COG: COG3711 Transcriptional antiterminator; Psort location: Cytoplasmic, score: 8.87.
    
  0.558
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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