STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepTPeptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (402 aa)    
Predicted Functional Partners:
EDS75543.1
Lipid kinase, YegS/Rv2252/BmrU family; KEGG: eci:UTI89_C2362 2.6e-17 hypothetical protein; COG: COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase.
       0.781
pflB
KEGG: bli:BL01863 5.4e-275 hypothetical formate acetyltransferase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98.
    
 
 0.653
EDS75145.1
Creatinase; KEGG: cpr:CPR_2506 5.8e-88 metallopeptidase, family M24 K01271; COG: COG0006 Xaa-Pro aminopeptidase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.652
mprF
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
     
 0.649
EDS75552.1
Hypothetical protein; KEGG: mxa:MXAN_0764 3.3e-18 peptidase, M24 (methionyl aminopeptidase 1) family K01423; COG: NOG08884 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.602
EDS75546.1
Nuclease-like protein; KEGG: efa:EF0511 2.0e-23 nuc-1; thermonuclease precursor K01174; COG: COG1525 Micrococcal nuclease (thermonuclease) homologs; Psort location: Extracellular, score: 10.00.
       0.530
EDS74818.1
KEGG: lmf:LMOf2365_0150 3.1e-215 inosine-5'-monophosphate dehydrogenase, putative K00088; COG: COG0516 IMP dehydrogenase/GMP reductase; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.520
rnhA
Ribonuclease HI; KEGG: cpr:CPR_1436 1.0e-35 RNAse H family protein K01163; COG: COG3341 Predicted double-stranded RNA/RNA-DNA hybrid binding protein; Psort location: Cytoplasmic, score: 8.87.
       0.519
EDS75746.1
Creatinase; KEGG: fnu:FN0453 5.4e-140 Xaa-Pro aminopeptidase K01262; COG: COG0006 Xaa-Pro aminopeptidase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.501
pyk-2
Pyruvate kinase; KEGG: ssp:SSP1069 2.9e-125 pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.483
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.