node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDS74119.1 | cysK | CLOSPI_01701 | CLOSPI_01707 | Putative dipeptidase; KEGG: lin:lin1661 5.6e-90 similar to Xaa-His dipeptidase K01439; COG: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; Psort location: Cytoplasmic, score: 8.87. | Cysteine synthase A; KEGG: cno:NT01CX_0572 1.6e-92 cysK; cysteine synthase A K01738; COG: COG0031 Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.663 |
EDS74119.1 | ddl | CLOSPI_01701 | CLOSPI_02505 | Putative dipeptidase; KEGG: lin:lin1661 5.6e-90 similar to Xaa-His dipeptidase K01439; COG: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; Psort location: Cytoplasmic, score: 8.87. | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.659 |
EDS74119.1 | glyA | CLOSPI_01701 | CLOSPI_02341 | Putative dipeptidase; KEGG: lin:lin1661 5.6e-90 similar to Xaa-His dipeptidase K01439; COG: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; Psort location: Cytoplasmic, score: 8.87. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.655 |
EDS74119.1 | hly | CLOSPI_01701 | CLOSPI_00606 | Putative dipeptidase; KEGG: lin:lin1661 5.6e-90 similar to Xaa-His dipeptidase K01439; COG: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; Psort location: Cytoplasmic, score: 8.87. | Hemolysin; KEGG: tde:TDE2410 4.8e-100 hemolysin K00842; COG: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; Psort location: Cytoplasmic, score: 8.87. | 0.418 |
EDS74119.1 | pepT | CLOSPI_01701 | CLOSPI_00581 | Putative dipeptidase; KEGG: lin:lin1661 5.6e-90 similar to Xaa-His dipeptidase K01439; COG: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; Psort location: Cytoplasmic, score: 8.87. | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.685 |
EDS74444.1 | glyA | CLOSPI_02028 | CLOSPI_02341 | Hydrogenase, Fe-only; KEGG: tte:TTE0894 1.4e-180 nuoG; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) K00336; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.680 |
EDS74444.1 | pepT | CLOSPI_02028 | CLOSPI_00581 | Hydrogenase, Fe-only; KEGG: tte:TTE0894 1.4e-180 nuoG; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) K00336; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87. | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.592 |
EDS74818.1 | EDS75145.1 | CLOSPI_01403 | CLOSPI_00973 | KEGG: lmf:LMOf2365_0150 3.1e-215 inosine-5'-monophosphate dehydrogenase, putative K00088; COG: COG0516 IMP dehydrogenase/GMP reductase; Psort location: Cytoplasmic, score: 8.87. | Creatinase; KEGG: cpr:CPR_2506 5.8e-88 metallopeptidase, family M24 K01271; COG: COG0006 Xaa-Pro aminopeptidase; Psort location: Cytoplasmic, score: 8.87. | 0.552 |
EDS74818.1 | EDS75552.1 | CLOSPI_01403 | CLOSPI_00589 | KEGG: lmf:LMOf2365_0150 3.1e-215 inosine-5'-monophosphate dehydrogenase, putative K00088; COG: COG0516 IMP dehydrogenase/GMP reductase; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; KEGG: mxa:MXAN_0764 3.3e-18 peptidase, M24 (methionyl aminopeptidase 1) family K01423; COG: NOG08884 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.552 |
EDS74818.1 | glyA | CLOSPI_01403 | CLOSPI_02341 | KEGG: lmf:LMOf2365_0150 3.1e-215 inosine-5'-monophosphate dehydrogenase, putative K00088; COG: COG0516 IMP dehydrogenase/GMP reductase; Psort location: Cytoplasmic, score: 8.87. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.563 |
EDS74818.1 | pepT | CLOSPI_01403 | CLOSPI_00581 | KEGG: lmf:LMOf2365_0150 3.1e-215 inosine-5'-monophosphate dehydrogenase, putative K00088; COG: COG0516 IMP dehydrogenase/GMP reductase; Psort location: Cytoplasmic, score: 8.87. | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.598 |
EDS75145.1 | EDS74818.1 | CLOSPI_00973 | CLOSPI_01403 | Creatinase; KEGG: cpr:CPR_2506 5.8e-88 metallopeptidase, family M24 K01271; COG: COG0006 Xaa-Pro aminopeptidase; Psort location: Cytoplasmic, score: 8.87. | KEGG: lmf:LMOf2365_0150 3.1e-215 inosine-5'-monophosphate dehydrogenase, putative K00088; COG: COG0516 IMP dehydrogenase/GMP reductase; Psort location: Cytoplasmic, score: 8.87. | 0.552 |
EDS75145.1 | pepT | CLOSPI_00973 | CLOSPI_00581 | Creatinase; KEGG: cpr:CPR_2506 5.8e-88 metallopeptidase, family M24 K01271; COG: COG0006 Xaa-Pro aminopeptidase; Psort location: Cytoplasmic, score: 8.87. | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.591 |
EDS75543.1 | pepT | CLOSPI_00580 | CLOSPI_00581 | Lipid kinase, YegS/Rv2252/BmrU family; KEGG: eci:UTI89_C2362 2.6e-17 hypothetical protein; COG: COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase. | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.781 |
EDS75552.1 | EDS74818.1 | CLOSPI_00589 | CLOSPI_01403 | Hypothetical protein; KEGG: mxa:MXAN_0764 3.3e-18 peptidase, M24 (methionyl aminopeptidase 1) family K01423; COG: NOG08884 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | KEGG: lmf:LMOf2365_0150 3.1e-215 inosine-5'-monophosphate dehydrogenase, putative K00088; COG: COG0516 IMP dehydrogenase/GMP reductase; Psort location: Cytoplasmic, score: 8.87. | 0.552 |
EDS75552.1 | pepT | CLOSPI_00589 | CLOSPI_00581 | Hypothetical protein; KEGG: mxa:MXAN_0764 3.3e-18 peptidase, M24 (methionyl aminopeptidase 1) family K01423; COG: NOG08884 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.640 |
cysK | EDS74119.1 | CLOSPI_01707 | CLOSPI_01701 | Cysteine synthase A; KEGG: cno:NT01CX_0572 1.6e-92 cysK; cysteine synthase A K01738; COG: COG0031 Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Putative dipeptidase; KEGG: lin:lin1661 5.6e-90 similar to Xaa-His dipeptidase K01439; COG: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; Psort location: Cytoplasmic, score: 8.87. | 0.663 |
cysK | ddl | CLOSPI_01707 | CLOSPI_02505 | Cysteine synthase A; KEGG: cno:NT01CX_0572 1.6e-92 cysK; cysteine synthase A K01738; COG: COG0031 Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.642 |
cysK | glyA | CLOSPI_01707 | CLOSPI_02341 | Cysteine synthase A; KEGG: cno:NT01CX_0572 1.6e-92 cysK; cysteine synthase A K01738; COG: COG0031 Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.718 |
cysK | hly | CLOSPI_01707 | CLOSPI_00606 | Cysteine synthase A; KEGG: cno:NT01CX_0572 1.6e-92 cysK; cysteine synthase A K01738; COG: COG0031 Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Hemolysin; KEGG: tde:TDE2410 4.8e-100 hemolysin K00842; COG: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; Psort location: Cytoplasmic, score: 8.87. | 0.885 |