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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnhARibonuclease HI; KEGG: cpr:CPR_1436 1.0e-35 RNAse H family protein K01163; COG: COG3341 Predicted double-stranded RNA/RNA-DNA hybrid binding protein; Psort location: Cytoplasmic, score: 8.87. (199 aa)    
Predicted Functional Partners:
EDS75546.1
Nuclease-like protein; KEGG: efa:EF0511 2.0e-23 nuc-1; thermonuclease precursor K01174; COG: COG1525 Micrococcal nuclease (thermonuclease) homologs; Psort location: Extracellular, score: 10.00.
       0.773
rnhB-2
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
    
 0.720
pepT
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
       0.519
EDS75543.1
Lipid kinase, YegS/Rv2252/BmrU family; KEGG: eci:UTI89_C2362 2.6e-17 hypothetical protein; COG: COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase.
       0.504
rnmV
Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.
 
     0.452
EDS75547.1
KEGG: rha:RHA1_ro09047 1.9e-41 ABC peptide transporter, permease component K02033; COG: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; Psort location: CytoplasmicMembrane, score: 10.00.
       0.427
oppC
COG: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; Psort location: CytoplasmicMembrane, score: 10.00.
       0.417
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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