Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EDS75577.1E1-E2 ATPase; KEGG: efa:EF1519 1.2e-153 cation-transporting ATPase, E1-E2 family; COG: COG0474 Cation transport ATPase; Psort location: CytoplasmicMembrane, score: 10.00. (781 aa)    
Predicted Functional Partners:
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
   0.529
EDS75576.1
Hypothetical protein; COG: NOG16848 non supervised orthologous group.
       0.469
EDS75578.1
SIS domain protein; KEGG: bam:Bamb_0825 8.6e-17 glucokinase K00845; COG: COG1737 Transcriptional regulators; Psort location: Cytoplasmic, score: 8.87.
  
    0.468
rpsH
Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
    
   0.460
rpsM
30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.
   
   0.458
EDS75771.1
SPFH/Band 7/PHB domain protein; KEGG: reh:H16_A2036 1.4e-52 membrane protease subunits, stomatin/prohibitin homologs K01423; COG: COG0330 Membrane protease subunits, stomatin/prohibitin homologs; Psort location: Cytoplasmic, score: 8.87.
   
  0.455
rpsE
Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
    
   0.455
rplD
50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
    
   0.451
cadA
Cadmium-exporting ATPase; KEGG: btk:BT9727_0506 3.5e-193 cation-transporting ATPase, P-type; COG: COG2217 Cation transport ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
 
 
0.444
rpsB
COG: COG0052 Ribosomal protein S2; Psort location: Cytoplasmic, score: 8.87; Belongs to the universal ribosomal protein uS2 family.
   
   0.432
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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