STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cutCCutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. (245 aa)    
Predicted Functional Partners:
EDS75590.1
Hypothetical protein; COG: COG0628 Predicted permease; Psort location: CytoplasmicMembrane, score: 9.75.
       0.773
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
   0.762
EDS75591.1
Hypothetical protein; KEGG: tbd:Tbd_2668 9.6e-10 phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthetase K01923; COG: COG0628 Predicted permease; Psort location: CytoplasmicMembrane, score: 9.99.
       0.752
EDS75592.1
Hypothetical protein; KEGG: mmy:MSC_0837 1.2e-39 pldB; lysophospholipase K01048; COG: COG2267 Lysophospholipase; Psort location: Cytoplasmic, score: 8.87.
       0.752
EDS75593.1
Acetyltransferase, GNAT family; KEGG: mma:MM3005 1.3e-21 acetyltransferase K00680; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: Cytoplasmic, score: 8.87.
       0.752
EDS74003.1
Asparaginase; KEGG: lsa:LSA1693 4.1e-87 asnA2; L-asparaginase K01424; COG: COG1446 Asparaginase; Psort location: Cytoplasmic, score: 8.87.
 
     0.690
EDS74594.1
Glycosyl hydrolase family 20, catalytic domain protein; KEGG: sco:SCO2786 7.0e-109 hexA, SCC105.17c; beta-N-acetylhexosaminidase K01207; COG: COG3525 N-acetyl-beta-hexosaminidase; Psort location: Extracellular, score: 9.95.
 
     0.683
EDS75594.1
Putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; KEGG: cac:CAC3596 2.8e-24 pgsA; phosphatidylglycerophosphate synthase K00995; COG: COG0558 Phosphatidylglycerophosphate synthase; Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.646
EDS75595.1
Hypothetical protein; KEGG: hdu:HD0030 0.00060 frdA; fumarate reductase flavoprotein subunit K00244; Psort location: Cytoplasmic, score: 8.87.
       0.646
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.579
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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