STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75290.1Putative transaminase; KEGG: sai:Saci_1837 9.0e-44 aspartate aminotransferase K00812; COG: COG0436 Aspartate/tyrosine/aromatic aminotransferase; Psort location: Cytoplasmic, score: 8.87. (369 aa)    
Predicted Functional Partners:
nifJ
KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.927
EDS75817.1
Class II glutamine amidotransferase; KEGG: syn:sll1502 0. gltB; NADH-dependent glutamate synthase large subunit K00268; COG: COG0069 Glutamate synthase domain 2; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.926
EDS74218.1
Chorismate mutase; KEGG: aae:aq_951 3.3e-53 pheA; chorismate mutase/prephenate dehydratase K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.870
EDS74574.1
FAD dependent oxidoreductase; KEGG: mma:MM1656 1.6e-55 oxidoreductase K00100; COG: COG0665 Glycine/D-amino acid oxidases (deaminating); Psort location: Cytoplasmic, score: 8.87.
  
 
 0.863
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.858
EDS75105.1
KEGG: ctc:CTC01806 2.7e-209 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; COG: COG1410 Methionine synthase I, cobalamin-binding domain; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.843
pyk-2
Pyruvate kinase; KEGG: ssp:SSP1069 2.9e-125 pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
   
 0.838
EDS75293.1
KEGG: hpa:HPAG1_1111 1.4e-15 glutamine ABC transporter, periplasmic glutamine-binding protein K05359; COG: COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Psort location: CytoplasmicMembrane, score: 9.87.
  
 
 0.807
EDS75291.1
KEGG: fnu:FN0801 2.1e-76 amino acid transport ATP-binding protein K02028; COG: COG1126 ABC-type polar amino acid transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
 
  
 0.781
EDS75292.1
ABC transporter, permease protein; KEGG: ret:RHE_PF00254 5.0e-29 glnP, glnQ; glutamine ABC transporter, ATP-binding protein K02028; COG: COG0765 ABC-type amino acid transport system, permease component; Psort location: CytoplasmicMembrane, score: 10.00.
       0.776
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.