STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75319.1Hypothetical protein; COG: NOG17660 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (153 aa)    
Predicted Functional Partners:
EDS75318.1
Transposase; COG: COG2963 Transposase and inactivated derivatives; Psort location: Cytoplasmic, score: 8.87.
       0.658
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.648
EDS74292.1
Hypothetical protein; KEGG: ctc:CTC01280 0.00025 polyribonucleotide nucleotidyltransferase K00962; Psort location: Cytoplasmic, score: 8.87.
 
      0.640
EDS75230.1
LysM domain protein; KEGG: aeh:Mlg_1995 5.1e-06 lytic transglycosylase, catalytic K08307; COG: COG3409 Putative peptidoglycan-binding domain-containing protein.
  
  
 0.521
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
    
 
 0.517
rplN
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
    
   0.516
EDS75317.1
Integrase core domain protein; KEGG: nwi:Nwi_0782 3.2e-10 integrase, catalytic region K00986; COG: COG2801 Transposase and inactivated derivatives; Psort location: Cytoplasmic, score: 8.87.
       0.497
EDS75320.1
KEGG: cno:NT01CX_1801 6.9e-14 noxC; nitroreductase family protein; COG: COG0778 Nitroreductase; Psort location: Cytoplasmic, score: 8.87.
       0.483
pyk
Pyruvate kinase; KEGG: oih:OB2171 3.5e-129 pykA; pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
    
   0.467
pyk-2
Pyruvate kinase; KEGG: ssp:SSP1069 2.9e-125 pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
    
   0.467
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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