Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDS75364.1O-methyltransferase; KEGG: bce:BC4378 2.7e-35 caffeoyl-CoA O-methyltransferase K00588; COG: COG4122 Predicted O-methyltransferase; Psort location: Cytoplasmic, score: 8.87. (198 aa)    
Predicted Functional Partners:
EDS75363.1
Peptidase, U32 family; KEGG: baa:BA_5051 1.0e-28 peptidase family U32 K08303; COG: COG0826 Collagenase and related proteases; Psort location: Cytoplasmic, score: 8.87.
  
 0.976
EDS75362.1
Peptidase, U32 family; KEGG: gka:GK2549 3.8e-116 protease K08303; COG: COG0826 Collagenase and related proteases; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.930
mltG
YceG family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
  
    0.814
EDS74929.1
Peptidase, U32 family; KEGG: ctc:CTC02275 5.4e-133 protease K08303; COG: COG0826 Collagenase and related proteases; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.664
greA
Prokaryotic transcription elongation factor, GreA/GreB domain protein; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
       0.587
EDS75487.1
Adenylate cyclase; KEGG: sar:SAR0971 6.8e-23 glutathione S-transferase K00799; COG: COG4116 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
  
     0.551
EDS75366.1
Hypothetical protein.
       0.516
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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