Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDS75404.1KEGG: ssp:SSP0322 1.7e-40 putative 6-O-methylguanine DNA methyltransferase K00567; COG: COG0350 Methylated DNA-protein cysteine methyltransferase; Psort location: Cytoplasmic, score: 8.87. (177 aa)    
Predicted Functional Partners:
EDS73978.1
Acetyltransferase, GNAT family; KEGG: lla:L170990 1.2e-41 yfhA; putative acetyltransferase K03827; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: Cytoplasmic, score: 8.87.
      0.898
tag
KEGG: tte:TTE0091 6.2e-52 tag; 3-Methyladenine DNA glycosylase K01246; COG: COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.
      0.866
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.480
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.460
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.426
EDS75405.1
Hypothetical protein; KEGG: hso:HS_1631 5.9e-08 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) K03775; COG: COG3906 Uncharacterized protein conserved in bacteria; Belongs to the UPF0473 family.
       0.413
EDS75406.1
RNAse H domain protein, YqgF family; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
       0.407
EDS75407.1
COG: COG4472 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
       0.406
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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