STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75476.1COG: COG1555 DNA uptake protein and related DNA-binding proteins; Psort location: Cytoplasmic, score: 8.87. (49 aa)    
Predicted Functional Partners:
EDS75475.1
DNA internalization competence protein ComEC/Rec2-like protein; KEGG: cel:ND6 0.00029 NADH dehydrogenase subunit 6 K03884; COG: COG0658 Predicted membrane metal-binding protein; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.920
holA
DNA polymerase III, delta subunit; KEGG: bld:BLi02748 5.4e-46 yqeN; similar to proteins; RBL00675 K02340; COG: COG1466 DNA polymerase III, delta subunit; Psort location: Cytoplasmic, score: 8.87.
     
 0.820
EDS75473.1
KEGG: bth:BT4678 3.0e-100 L-serine dehydratase K01752; COG: COG1760 L-serine deaminase; Psort location: Cytoplasmic, score: 8.87.
       0.800
EDS75472.1
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.791
EDS74963.1
Bacterial type II secretion system domain protein F; COG: COG1459 Type II secretory pathway, component PulF; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.762
EDS74964.1
KEGG: pen:PSEEN2333 1.1e-38 xcpR-2; type II secretion pathway protein E K01509; COG: COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; Psort location: Cytoplasmic, score: 9.36.
  
  
 0.688
comFA
ComF operon protein 1; KEGG: erw:ERWE_CDS_00310 4.1e-09 recG; ATP-dependent DNA helicase RecG K03655; COG: COG4098 Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein).
   
  
 0.672
EDS75838.1
Bacterial peptidase A24, N-terminal domain protein; KEGG: ctc:CTC02411 1.1e-36 pilD; type IV prepilin leader peptidase pilD K02654; COG: COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; Psort location: CytoplasmicMembrane, score: 10.00.
   
  
 0.655
EDS74209.1
Acyltransferase; KEGG: ctc:CTC00551 1.7e-26 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655; COG: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Psort location: Cytoplasmic, score: 8.87.
 
  
  0.651
EDS74962.1
Prepilin-type cleavage/methylation N-terminal domain protein; COG: COG4537 Competence protein ComGC.
   
  
 0.637
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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