rpmA protein (Clostridium spiroforme) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

rpmA

COG: COG0211 Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. (94 aa)

Predicted Functional Partners:

rplU

0.999

rpsP

0.996

cgtA

0.995

rplQ

0.993

rplM

0.992

EDS75057.1

0.992

rplS

0.992

rpsI

0.991

rplT

0.990

rpsD

0.990

Your Current Organism:

Clostridium spiroforme

NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDS75057.1	cgtA	CLOSPI_00883	CLOSPI_00881	Hypothetical protein; KEGG: pha:PSHAa2725 0.0056 maeB; NADP-dependent malic enzyme (NADP-dependent malic oxidoreductase (N-terminal); phosphotransacetylase (C-terminal)) K00029; COG: COG2868 Predicted ribosomal protein.	Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	0.648
EDS75057.1	rplM	CLOSPI_00883	CLOSPI_00214	Hypothetical protein; KEGG: pha:PSHAa2725 0.0056 maeB; NADP-dependent malic enzyme (NADP-dependent malic oxidoreductase (N-terminal); phosphotransacetylase (C-terminal)) K00029; COG: COG2868 Predicted ribosomal protein.	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.472
EDS75057.1	rplS	CLOSPI_00883	CLOSPI_01188	Hypothetical protein; KEGG: pha:PSHAa2725 0.0056 maeB; NADP-dependent malic enzyme (NADP-dependent malic oxidoreductase (N-terminal); phosphotransacetylase (C-terminal)) K00029; COG: COG2868 Predicted ribosomal protein.	Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.520
EDS75057.1	rplU	CLOSPI_00883	CLOSPI_00884	Hypothetical protein; KEGG: pha:PSHAa2725 0.0056 maeB; NADP-dependent malic enzyme (NADP-dependent malic oxidoreductase (N-terminal); phosphotransacetylase (C-terminal)) K00029; COG: COG2868 Predicted ribosomal protein.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.964
EDS75057.1	rpmA	CLOSPI_00883	CLOSPI_00882	Hypothetical protein; KEGG: pha:PSHAa2725 0.0056 maeB; NADP-dependent malic enzyme (NADP-dependent malic oxidoreductase (N-terminal); phosphotransacetylase (C-terminal)) K00029; COG: COG2868 Predicted ribosomal protein.	COG: COG0211 Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.992
EDS75057.1	rpsD	CLOSPI_00883	CLOSPI_01084	Hypothetical protein; KEGG: pha:PSHAa2725 0.0056 maeB; NADP-dependent malic enzyme (NADP-dependent malic oxidoreductase (N-terminal); phosphotransacetylase (C-terminal)) K00029; COG: COG2868 Predicted ribosomal protein.	Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.574
EDS75057.1	rpsI	CLOSPI_00883	CLOSPI_00215	Hypothetical protein; KEGG: pha:PSHAa2725 0.0056 maeB; NADP-dependent malic enzyme (NADP-dependent malic oxidoreductase (N-terminal); phosphotransacetylase (C-terminal)) K00029; COG: COG2868 Predicted ribosomal protein.	COG: COG0103 Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.420
EDS75057.1	rpsP	CLOSPI_00883	CLOSPI_01183	Hypothetical protein; KEGG: pha:PSHAa2725 0.0056 maeB; NADP-dependent malic enzyme (NADP-dependent malic oxidoreductase (N-terminal); phosphotransacetylase (C-terminal)) K00029; COG: COG2868 Predicted ribosomal protein.	COG: COG0228 Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.400
cgtA	EDS75057.1	CLOSPI_00881	CLOSPI_00883	Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	Hypothetical protein; KEGG: pha:PSHAa2725 0.0056 maeB; NADP-dependent malic enzyme (NADP-dependent malic oxidoreductase (N-terminal); phosphotransacetylase (C-terminal)) K00029; COG: COG2868 Predicted ribosomal protein.	0.648
cgtA	rplM	CLOSPI_00881	CLOSPI_00214	Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.891
cgtA	rplQ	CLOSPI_00881	CLOSPI_01596	Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	COG: COG0203 Ribosomal protein L17; Psort location: Cytoplasmic, score: 8.87.	0.912
cgtA	rplS	CLOSPI_00881	CLOSPI_01188	Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.915
cgtA	rplT	CLOSPI_00881	CLOSPI_00539	Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.963
cgtA	rplU	CLOSPI_00881	CLOSPI_00884	Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.982
cgtA	rpmA	CLOSPI_00881	CLOSPI_00882	Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	COG: COG0211 Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.995
rplM	EDS75057.1	CLOSPI_00214	CLOSPI_00883	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Hypothetical protein; KEGG: pha:PSHAa2725 0.0056 maeB; NADP-dependent malic enzyme (NADP-dependent malic oxidoreductase (N-terminal); phosphotransacetylase (C-terminal)) K00029; COG: COG2868 Predicted ribosomal protein.	0.472
rplM	cgtA	CLOSPI_00214	CLOSPI_00881	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	0.891
rplM	rplQ	CLOSPI_00214	CLOSPI_01596	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	COG: COG0203 Ribosomal protein L17; Psort location: Cytoplasmic, score: 8.87.	0.993
rplM	rplS	CLOSPI_00214	CLOSPI_01188	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.989
rplM	rplT	CLOSPI_00214	CLOSPI_00539	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.995