Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
gerESpore germination protein GerE; KEGG: fal:FRAAL1304 6.7e-09 putative protein-glutamate methylesterase; COG: COG2771 DNA-binding HTH domain-containing proteins; Psort location: Cytoplasmic, score: 9.98. (67 aa)    
Predicted Functional Partners:
EDS75826.1
Histidine kinase; KEGG: btl:BALH_1575 1.1e-29 sensor histidine kinase; COG: COG4585 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
 
 
 0.743
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
     
 0.672
mutS2
MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
       0.639
EDS75088.1
Putative CvpA family protein; COG: COG1286 Uncharacterized membrane protein, required for colicin V production; Psort location: CytoplasmicMembrane, score: 9.99.
       0.639
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
  
  
 0.628
EDS75084.1
Serine-type D-Ala-D-Ala carboxypeptidase; KEGG: bha:BH1810 3.6e-20 D-alanyl-D-alanine carboxypeptidase K07260; COG: COG1876 D-alanyl-D-alanine carboxypeptidase; Psort location: Cytoplasmic, score: 9.36.
       0.592
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.465
EDS75082.1
COG: COG5401 Spore germination protein; Psort location: Cytoplasmic, score: 8.87.
       0.459
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.455
EDS75817.1
Class II glutamine amidotransferase; KEGG: syn:sll1502 0. gltB; NADH-dependent glutamate synthase large subunit K00268; COG: COG0069 Glutamate synthase domain 2; Psort location: Cytoplasmic, score: 8.87.
     
 0.446
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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