STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (259 aa)    
Predicted Functional Partners:
recU
Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
  
   
 0.752
EDS75487.1
Adenylate cyclase; KEGG: sar:SAR0971 6.8e-23 glutathione S-transferase K00799; COG: COG4116 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
  
     0.714
EDS74917.1
COG: COG3763 Uncharacterized protein conserved in bacteria.
 
     0.701
rnhB-2
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
    
 0.690
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
     
 0.678
mutS2
MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
       0.634
EDS75129.1
Putative septation ring formation regulator EzrA; KEGG: fnu:FN0522 3.9e-11 exonuclease SBCC K03546; COG: COG4477 Negative regulator of septation ring formation; Psort location: Cytoplasmic, score: 8.87.
  
    0.628
EDS75088.1
Putative CvpA family protein; COG: COG1286 Uncharacterized membrane protein, required for colicin V production; Psort location: CytoplasmicMembrane, score: 9.99.
     
 0.583
EDS76014.1
Putative ACR, COG1399; COG: COG1399 Predicted metal-binding, possibly nucleic acid-binding protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.582
EDS74133.1
COG: COG4476 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
  
     0.571
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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