STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75113.1Molybdopterin binding domain protein; KEGG: mmu:319945 0.00014 Flad1; RFad1, flavin adenine dinucleotide synthetase, homolog (yeast) K00953; COG: COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Psort location: Cytoplasmic, score: 8.87. (352 aa)    
Predicted Functional Partners:
EDS74810.1
Competence/damage-inducible domain protein CinA; COG: COG1546 Uncharacterized protein (competence- and mitomycin-induced); Psort location: Cytoplasmic, score: 8.87; Belongs to the CinA family.
  
 0.993
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.935
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.928
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
 
 0.922
nadC
Nicotinate-nucleotide diphosphorylase (carboxylating); KEGG: cpe:CPE0396 1.0e-81 nadC; nicotinate-nucleotide pyrophosphorylase K00767; COG: COG0157 Nicotinate-nucleotide pyrophosphorylase; Psort location: Cytoplasmic, score: 9.65; Belongs to the NadC/ModD family.
    
 0.905
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
    
  0.899
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
 
  
 0.896
EDS74572.1
FAD binding domain protein; KEGG: cpr:CPR_0377 8.4e-112 nadB; L-aspartate oxidase K00278; COG: COG0029 Aspartate oxidase; Psort location: Cytoplasmic, score: 9.36.
    
 0.891
EDS75546.1
Nuclease-like protein; KEGG: efa:EF0511 2.0e-23 nuc-1; thermonuclease precursor K01174; COG: COG1525 Micrococcal nuclease (thermonuclease) homologs; Psort location: Extracellular, score: 10.00.
    
  0.878
EDS75703.1
Hypothetical protein; KEGG: mpn:MPN473 2.3e-07 lip2, P01_orf268; triacylglycerol lipase (lip) 2; COG: COG1073 Hydrolases of the alpha/beta superfamily; Psort location: Cytoplasmic, score: 8.87.
  
 
  0.875
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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