STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75131.1Phosphogluconate dehydrogenase (decarboxylating), NAD binding domain protein; KEGG: cpe:CPE0393 5.2e-80 3-hydroxyisobutyrate dehydrogenase K00020; COG: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; Psort location: Cytoplasmic, score: 8.87. (287 aa)    
Predicted Functional Partners:
EDS75666.1
KEGG: chy:CHY_0128 4.3e-76 fba; fructose-1,6-bisphosphate aldolase, class II K01624; COG: COG0191 Fructose/tagatose bisphosphate aldolase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.890
fba
KEGG: cpf:CPF_1557 3.4e-115 fba; fructose-1,6-bisphosphate aldolase, class II K01624; COG: COG0191 Fructose/tagatose bisphosphate aldolase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.885
EDS75030.1
KEGG: cno:NT01CX_0234 4.8e-116 citrate synthase I K01647; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.834
pflB
KEGG: bli:BL01863 5.4e-275 hypothetical formate acetyltransferase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98.
   
 
  0.802
EDS75130.1
Peptidase C26; KEGG: fnu:FN0505 5.5e-28 anthranilate synthase component II K01656; COG: COG2071 Predicted glutamine amidotransferases.
       0.773
EDS74629.1
Alcohol dehydrogenase, iron-dependent; KEGG: msu:MS2190 0. eutG; alcohol dehydrogenase IV K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.606
EDS75129.1
Putative septation ring formation regulator EzrA; KEGG: fnu:FN0522 3.9e-11 exonuclease SBCC K03546; COG: COG4477 Negative regulator of septation ring formation; Psort location: Cytoplasmic, score: 8.87.
       0.532
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
       0.465
EDS75128.1
Aminotransferase, class V; KEGG: oih:OB2199 9.8e-86 L-cysteine sulfurtransferase (iron-sulfur cofactor synthesis) K04487; COG: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; Psort location: Cytoplasmic, score: 8.87.
  
    0.459
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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