Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDS75176.1NAD dependent epimerase/dehydratase family protein; KEGG: vfi:VF0192 4.6e-72 UDP-2-acetamido-2,6-dideoxy-beta-L-talose 4-dehydrogenase K00100; COG: COG0451 Nucleoside-diphosphate-sugar epimerases; Psort location: Cytoplasmic, score: 8.87. (399 aa)    
Predicted Functional Partners:
EDS75173.1
KEGG: spn:SP_0360 5.5e-179 UDP-N-acetylglucosamine 2-epimerase K01791; COG: COG0381 UDP-N-acetylglucosamine 2-epimerase; Psort location: Cytoplasmic, score: 8.87.
 
 0.973
EDS75185.1
Polysaccharide biosynthesis protein; KEGG: saa:SAUSA300_0156 4.8e-109 cap5E; capsular polysaccharide biosynthesis protein Cap5E K01726; COG: COG1086 Predicted nucleoside-diphosphate sugar epimerases; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.965
EDS75368.1
KEGG: spn:SP_0360 3.0e-178 UDP-N-acetylglucosamine 2-epimerase K01791; COG: COG0381 UDP-N-acetylglucosamine 2-epimerase; Psort location: Cytoplasmic, score: 8.87.
 
 0.955
EDS74359.1
KEGG: spn:SP_0360 3.9e-178 UDP-N-acetylglucosamine 2-epimerase K01791; COG: COG0381 UDP-N-acetylglucosamine 2-epimerase; Psort location: Cytoplasmic, score: 8.87.
 
 0.955
EDS74357.1
Polysaccharide biosynthesis protein; KEGG: saa:SAUSA300_0156 1.1e-111 cap5E; capsular polysaccharide biosynthesis protein Cap5E K01726; COG: COG1086 Predicted nucleoside-diphosphate sugar epimerases; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.950
EDS74358.1
NAD dependent epimerase/dehydratase family protein; KEGG: vfi:VF0192 6.5e-73 UDP-2-acetamido-2,6-dideoxy-beta-L-talose 4-dehydrogenase K00100; COG: COG0451 Nucleoside-diphosphate-sugar epimerases.
 
 
0.927
EDS75375.1
Nucleotide sugar dehydrogenase; KEGG: tdn:Tmden_1968 1.4e-150 UDP-glucose 6-dehydrogenase K00012; COG: COG1004 Predicted UDP-glucose 6-dehydrogenase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.901
rfbD
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
  
 
 0.881
rfbA-2
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
  
 0.876
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
 0.798
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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