Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDS75208.1Riboflavin biosynthesis protein RibD C-terminal domain protein; KEGG: mja:MJ0671 1.4e-15 5-amino-6-(5-phosphoribosylamino)uracil reductase K00082; COG: COG1985 Pyrimidine reductase, riboflavin biosynthesis. (241 aa)    
Predicted Functional Partners:
EDS75209.1
Cupin domain protein; COG: COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.
 
    0.813
EDS75207.1
Flavodoxin; COG: COG0716 Flavodoxins.
       0.774
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
   0.600
eno-2
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
   0.600
EDS75210.1
Hypothetical protein; KEGG: bcc:BCc_198 0.0039 pykA; PykA K00873; Psort location: Cytoplasmic, score: 8.87.
       0.512
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
  
  
 0.482
EDS75206.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.480
EDS75950.1
ATP-grasp domain protein; KEGG: cpe:CPE0819 2.0e-05 ddlB; D-alanine-D-alanine ligase K01921; COG: NOG08747 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
 
   0.467
EDS75948.1
Hypothetical protein; KEGG: aae:aq_742 2.3e-05 purD; phosphoribosylamine-glycine ligase K01945; COG: NOG08747 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
 
   0.463
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.460
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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