STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75208.1Riboflavin biosynthesis protein RibD C-terminal domain protein; KEGG: mja:MJ0671 1.4e-15 5-amino-6-(5-phosphoribosylamino)uracil reductase K00082; COG: COG1985 Pyrimidine reductase, riboflavin biosynthesis. (241 aa)    
Predicted Functional Partners:
EDS75209.1
Cupin domain protein; COG: COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.
 
     0.811
pyk-2
Pyruvate kinase; KEGG: ssp:SSP1069 2.9e-125 pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
   
 
  0.801
EDS75207.1
Flavodoxin; COG: COG0716 Flavodoxins.
       0.779
hisE
phosphoribosyl-ATP diphosphatase; KEGG: lla:L0072 1.5e-80 hisI; phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase K01496:K01523; COG: COG0139 Phosphoribosyl-AMP cyclohydrolase; Psort location: Cytoplasmic, score: 9.98; In the N-terminal section; belongs to the PRA-CH family.
    
 0.558
EDS75950.1
ATP-grasp domain protein; KEGG: cpe:CPE0819 2.0e-05 ddlB; D-alanine-D-alanine ligase K01921; COG: NOG08747 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
 
   0.528
EDS75948.1
Hypothetical protein; KEGG: aae:aq_742 2.3e-05 purD; phosphoribosylamine-glycine ligase K01945; COG: NOG08747 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
 
   0.525
EDS75210.1
Hypothetical protein; KEGG: bcc:BCc_198 0.0039 pykA; PykA K00873; Psort location: Cytoplasmic, score: 8.87.
       0.512
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
  
  
 0.501
EDS75206.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.480
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
    0.443
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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